Hypocalcemic seizure caused by vitamin D deficiency in infant

We described the case of a 2-month-old child was presented to the emergency department with a generalized seizure, which started 40 days after birth. The laboratory examination revealed hypocalcemia (3.4 mg/dL), normal albumin serum, elevated PTH level of 235.9 pg/mL, decreased vitamin D of 13.8 ng/...

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Main Authors: Fatimah Arief, -, Nur Rochmah, -, Muhammad Faizi, -, Prastiya Indra Gunawan, -, Riza Noviandi, -
Format: Article PeerReviewed
Language:English
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English
Published: Renaissance Medical Publishing 2022
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Online Access:https://repository.unair.ac.id/126821/1/28%20-%20Artikel.pdf
https://repository.unair.ac.id/126821/2/28%20-%20Korespondensi.pdf
https://repository.unair.ac.id/126821/3/28%20-%20Kualitas%20Karil.pdf
https://repository.unair.ac.id/126821/4/28%20-%20Turnitin.pdf
https://repository.unair.ac.id/126821/
https://sciencescholar.us/journal/index.php/ijhs/article/view/12342
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Institution: Universitas Airlangga
Language: English
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Summary:We described the case of a 2-month-old child was presented to the emergency department with a generalized seizure, which started 40 days after birth. The laboratory examination revealed hypocalcemia (3.4 mg/dL), normal albumin serum, elevated PTH level of 235.9 pg/mL, decreased vitamin D of 13.8 ng/dL, and normal renal function. The mother had not consumed vitamin D supplement during pregnancy and lactation. The patient had also been consuming phenobarbital since the age of 1 month due to a previous history of seizures. The disease was managed with oral administration of 10% calcium gluconate along with 5000 IU of vitamin D3 daily to manage calcium homeostasis. The treatment stabilized the patient's condition and there was rapid improvement in laboratory findings. After 6 months, the seizure disappeared and the level of vitamin D (25- hydroxy vitamin D) was normal, namely 80 ng/dL.