Hypocalcemic seizure caused by vitamin D deficiency in infant

• Main Authors: Fatimah Arief, -, Nur Rochmah, -, Muhammad Faizi, -, Prastiya Indra Gunawan, -, Riza Noviandi, -
• Format: Article PeerReviewed
• Language: English; English; English; English; English
• Published: Renaissance Medical Publishing 2022
• Subjects: R Medicine (General); RJ Pediatrics
• Online Access: https://repository.unair.ac.id/126895/1/28%20-%20Artikel.pdf; https://repository.unair.ac.id/126895/2/28%20-%20Korespondensi.pdf; https://repository.unair.ac.id/126895/3/28%20-%20Kualitas%20Karil.pdf; https://repository.unair.ac.id/126895/4/28%20-%20Turnitin.pdf; https://repository.unair.ac.id/126895/8/Karil%20-%20Hypocalcemic%20Seizure%20Caused%20by%20Vitamin%20D%20Deficiency%20in%20Infant.pdf; https://repository.unair.ac.id/126895/; https://sciencescholar.us/journal/index.php/ijhs/article/view/12342
• Institution: Universitas Airlangga

We described the case of a 2-month-old child was presented to the emergency department with a generalized seizure, which started 40 days after birth. The laboratory examination revealed hypocalcemia (3.4 mg/dL), normal albumin serum, elevated PTH level of 235.9 pg/mL, decreased vitamin D of 13.8 ng/dL, and normal renal function. The mother had not consumed vitamin D supplement during pregnancy and lactation. The patient had also been consuming phenobarbital since the age of 1 month due to a previous history of seizures. The disease was managed with oral administration of 10% calcium gluconate along with 5000 IU of vitamin D3 daily to manage calcium homeostasis. The treatment stabilized the patient's condition and there was rapid improvement in laboratory findings. After 6 months, the seizure disappeared and the level of vitamin D (25- hydroxy vitamin D) was normal, namely 80 ng/dL.