Mechanism of the Bioactive Sargassum cristaefolium in Inhibiting Inflammatory Mediators in a Nitroglycerin-Induced Migraine Model in Rats

• Main Authors: Olivia Mahardani Adam, -, Jusak Nugraha, -, Muhammad Hamdan, Muhammad, Agus Turchan, -
• Format: Article PeerReviewed
• Language: English; Indonesian; English; Indonesian
• Published: Pharmacognosy Network Worldwide
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/127727/1/12.%20Mechanism%20of%20the%20Bioactive_removed.pdf; https://repository.unair.ac.id/127727/2/12.%20Mechanism%20of%20the%20Bioactive.pdf; https://repository.unair.ac.id/127727/3/12.%20Mechanism%20of%20the%20Bioactive.pdf; https://repository.unair.ac.id/127727/6/12%20etik.pdf; https://repository.unair.ac.id/127727/; https://www.phcogj.com/article/1779; http://dx.doi.org/10.5530/pj.2022.14.50
• Institution: Universitas Airlangga

Abstract: Background: Migraine headaches are a form of sterile neurogenic inflammation. The sterile inflammatory process of the trigeminal nerve releases the vasoactive neuropeptide CGRP which stimulates the release of inflammatory mediators. In the incidence of migraine there is an increase in TNF...