Correlation between Blood and Cerebrospinal Fluid (CSF) Neutrophil-Lymphocyte Ratio with Bacterial Meningitis Prognosis Patient
Abstract Bacterial Meningitis is a bacterial infection of the central nervous system’s protective membranes called the meninges. Bacterial Meningitis has a high disability and case fatality rate. This inflammatory process not only manifests in CSF but also systemically. The neutrophil-lymphocyte ra...
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| Main Authors: | , , , |
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| Format: | Article PeerReviewed |
| Language: | English Indonesian English Indonesian |
| Published: |
Universitas Aisyah Pringsewu (UAP) Lampung
2023
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| Subjects: | |
| Online Access: | https://repository.unair.ac.id/128109/1/12.%20Correlation.pdf https://repository.unair.ac.id/128109/2/12.pdf https://repository.unair.ac.id/128109/3/12.%20Correlation.pdf https://repository.unair.ac.id/128109/4/12.pdf https://repository.unair.ac.id/128109/ https://aisyah.journalpress.id/index.php/jika/article/view/8267 http://dx.doi.org/10.30604/jika.v8i2.1993 |
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| Institution: | Universitas Airlangga |
| Language: | English Indonesian English Indonesian |
| Summary: | Abstract
Bacterial Meningitis is a bacterial infection of the central nervous system’s protective membranes called the meninges. Bacterial Meningitis has a high disability and case fatality rate. This inflammatory process not only manifests in CSF but also systemically. The neutrophil-lymphocyte ratio(NLR) can be a predicting factor of severity and prognosis in systemic inflammation. Only a few studies in Indonesia evaluate the neutrophil-lymphocyte ratio as a predictor of mortality in adult bacterial meningitis. This study also aimed to compare neutrophil-lymphocyte ratio in LCS and systemic as a predictor of mortality in patients with adult bacterial meningitis. This is an analytic cross-sectional study in Dr. Soetomo's general hospital—a total sample of 44 bacterial meningitis patients from the inpatient ward of Dr. Soetomo General Hospital Surabaya. The blood Neutrophil- Lymphocyte ratio, Glasgow Coma Scale upon admission, and Absolute lymphocyte count were significant with bacterial meningitis outcome with p-value less than 0.05. Early detection of bacterial meningitis patient prognosis could alert the healthcare provider to give careful monitoring and aggressive treatment. |
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