Clinacanthus nutans L Extracts Reduce the Serum Tumor Necrosis Factor-α, Malondialdehyde, and Interleukin-6 Levels and Improve the Langerhans Islet Area in Diabetic Rat Models

• Main Authors: Arifa Mustika, Arifa, Nurmawati Fatimah, -, Indri Safitri Mukono, -, Nurlaili Susanti, -, Nurul Shahfiza Noor, -
• Format: Article PeerReviewed
• Language: English; English; English; English; English
• Published: SAGE 2023
• Subjects: R Medicine
• Online Access: https://repository.unair.ac.id/128125/1/Artikel%20Tambahan%202.pdf; https://repository.unair.ac.id/128125/2/Karil%202.pdf; https://repository.unair.ac.id/128125/4/Turnitin%20Tambahan%202.pdf; https://repository.unair.ac.id/128125/3/KORESPONDENSI%2002.pdf; https://repository.unair.ac.id/128125/10/Etik%20Clinacanthus%20nutans.pdf; https://repository.unair.ac.id/128125/; https://journals.sagepub.com/doi/epub/10.1177/11795514231196462; https://doi.org/10.1177/11795514231196462
• Institution: Universitas Airlangga

BACKGROUND: Diabetes mellitus-induced hyperglycemia increases oxidative stress and inflammatory cytokine production, which play a significant role in the damage and apoptosis of pancreatic p cells. Therefore, the administration of medications that can reduce oxidative stress and inflammation plays a...