The Relationship Between Plasma Vitamin D and Severity of Critical Disease Patients Admitted to the Intensive Care Unit

• Main Authors: Pirhot L. M. Y. Siahaan, -, Anna Surgean Veterini, Anna, Bambang Pujo Semedi, -, Prananda Surya Airlangga, -, Edward Kusuma, -, Irwanto, -
• Format: Article PeerReviewed
• Language: English; Indonesian; English
• Published: Mediscript Ltd
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/128414/1/16.%20The%20Relationship%20Between%20Plasma%20Vitamin%20D.pdf; https://repository.unair.ac.id/128414/2/KARIL%20The%20Relationship%20Between%20Plasma%20Vitamin%20D.pdf; https://repository.unair.ac.id/128414/3/16%20turnitin.pdf; https://repository.unair.ac.id/128414/; https://hivnursing.net/index.php/hiv/article/view/1988; https://doi.org/10.31838/hiv23.03.221
• Institution: Universitas Airlangga

Abstract Introduction: Vitamin D is a micro-nutrient component that deserves to be taken into consideration for its various functions. In addition, according to various sources, it is said that vitamin D also has a role in the progress of critical patient conditions. Vitamin D deficiency condition often occurs not only in general patients but also in critical patients. Vitamin D deficiency in critically ill patients can be caused by a number of co-morbidities, systemic inflammation and multiorgan failure. Aim and Objective: The purpose of this study was to determine the relationship between plasma levels of vitamin D and the severity of the disease in critically ill patients treated in the Intensive Care Unit. Materials and Methods: This research is an observational analytic research. This research was conducted in the Intensive Care Unit of Dr. Soetomo Hospital Surabaya. The sample in this study were 32 people according to the inclusion and exclusion criteria. Data will be analyzed descriptive analytically. Results and Conclusion: The result showed that patient profiles, such as: age, gender, comorbidity status, smoking history, sun exposure, milk consumption, supplement or multivitamin consumption, BMI, SOFA Score, and APACHE II have significant differences between mild, moderate, and optimal levels of vitamin D deficiency (p=0.001). We hypothesized that nutrition has an effect on plasma vitamin D levels, but this research did not show a significant relationship between fish consumption and plasma vitamin D levels. Fish consumption had no significant difference (p=0.371). There was a significant negative correlation between vitamin D and SOFA score (p<0.001) and APACHE II (p<0.001). The critical patients profile in Dr Soetomo Hospital shows that mostly <50 years old, female, no history of smoking, exposed to sunlight >30 minutes, consumed fish, did not consume milk, and consumed supplements or multivitamins. The most common vitamin D levels in critically ill patients admitted to the Intensive Care Unit were optimal. The severity of critical illness patients based on SOFA Score between 0-1 and ≥ 2 is relatively similar. While based on APACHE II the most are 0-4. There is a significant relationship between vitamin D levels and the severity of critical illness patients treated in the intensive care unit according to SOFA Score and APACHE II.