Association between single nucleotide polymorphism SLCO1B1 gene and simvastatin pleiotropic effects measured through flow-mediated dilation endothelial function parameters

• Main Authors: Andrianto, -, Mia Puspitasari, -, Meity Ardiana, Meity, Ivana Purnama Dewi, -, Khubay Alvia Shonafi, -, Louisa Fadjri Kusuma Wardhani, -, Ricardo Adrian Nugraha, -
• Format: Article PeerReviewed
• Language: English; English; English; Indonesian
• Published: SAGE 2022
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/128434/1/14.%20Association%20between%20singel%20nucleotide.pdf; https://repository.unair.ac.id/128434/3/14.%20Association%20between%20singel%20nucleotide.pdf; https://repository.unair.ac.id/128434/4/14%20koresponden.pdf; https://repository.unair.ac.id/128434/9/12.%20karil.pdf; https://repository.unair.ac.id/128434/; https://pubmed.ncbi.nlm.nih.gov/36314075/; https://doi.org/10.1177/17539447221132367
• Institution: Universitas Airlangga

Abstract Background: Atherosclerosis is a condition in which the medium to large arteries become inflamed over time. The cornerstone to the atherosclerosis process is endothelial dysfunction. Simvastatin is a cholesterol-lowering drug known for its endothelial cell pleiotropic properties. The role...