Uji Stabilitas Hemaglutinin dan Daya Infeksi Virus Avian Influenza A/Ck/Indonesia/Bl/2003(H5n1) terhadap Pemanasan
One of the two glycoproteins on the surface of the influenza virus particle had been identified as hemagglutinin. These proteins involved in the process of virus attachment to host cells and also functioned as a determinant of the pathogenicity level. From the aspect of disease control, haemagglu...
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| Main Author: | |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://repository.unair.ac.id/129775/1/KKC%20KK%20SKH%20Sar%20u.pdf https://repository.unair.ac.id/129775/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian |
| Summary: | One of the two glycoproteins on the surface of the influenza virus particle
had been identified as hemagglutinin. These proteins involved in the process of
virus attachment to host cells and also functioned as a determinant of the
pathogenicity level. From the aspect of disease control, haemagglutinin may be
used as a vaccine. Given the important role of haemagglutinin, knowledge of the
characterization which was also the goal of this research was needed. Researcher
used a virus isolate that isolates AlCkllndonesiaIBLl2003 which will be tested for
stability and infection ability towards the heating at 55°C, 60°C, 65°C and 70°C
and time for 1 minute, 3 minutes, 5 minutes, 10 minutes, 15 minutes, 20 minutes,
30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes and 150
minutes. The results showed that the isolates AlCklIndonesialBLl2003 was not
stable against heating at 55°C for 30 minutes and 60°C for 5 minutes.
Hemaglutinin on the surface of the virus will be danaturated after heating thus
losing it's ability to infect host cells. |
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