Selenium level correlates negatively with antibodies but positively with thyroid function in children with down syndrome: an Indonesian study

• Main Authors: Yuni Hisbiyah, -, Anang Endaryanto, -, Bagus Setyoboedi, Bagus, Nur Rochmah, -, Muhammad Faizi, -, Katherine Fedora, -
• Format: Article PeerReviewed
• Language: English; Indonesian; English; Indonesian
• Published: Frontiers Media S.A. 2023
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/130005/1/05.%20artikel.pdf; https://repository.unair.ac.id/130005/2/5%20karil.pdf; https://repository.unair.ac.id/130005/3/05.%20turnitin.pdf; https://repository.unair.ac.id/130005/7/06.%20etik.pdf; https://repository.unair.ac.id/130005/; https://www.frontiersin.org/articles/10.3389/fendo.2023.1177373/full; https://doi.org/10.3389/fendo.2023.1177373
• Institution: Universitas Airlangga

Background: Children with Down syndrome (DS) are prone to developing autoimmune thyroid disease (AITD). Previous studies found lower selenium (Se) levels in children with AITD. Glutathione peroxidase-3 (GPx3) and selenoprotein-P (SePP) are widely used to measure Se levels. DS children tend to have l...