The effect of metformin on autophagy by LC3 expression in Type 2 Diabetes Mellitus (T2DM) human skeletal muscle cell culture

• Main Authors: Jongky Hendro Prajitno, -, Agung Pranoto, -, Robert Dwitama Adiwinoto, -, Soebagijo Adi Soelistijo, Soebagijo
• Format: Article PeerReviewed
• Language: English; Indonesian; English
• Published: Sanglah General Hospital
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/130923/1/12.%20Artikel.pdf; https://repository.unair.ac.id/130923/2/12%20karil.pdf; https://repository.unair.ac.id/130923/3/12.%20turnitin.pdf; https://repository.unair.ac.id/130923/; https://www.balimedicaljournal.org/index.php/bmj/article/view/3203; https://doi.org/10.15562/bmj.v11i1.3203
• Institution: Universitas Airlangga

Abstract Background: Skeletal muscle is an essential tissue in glucose metabolism. Reduced autophagic capacity to remove damaged contractile proteins in skeletal muscle cells will contribute to the loss of muscle mass. Metformin is the first-line agent for treating type 2 diabetes mellitus (T2DM) p...