Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients

• Main Authors: Yan Efrata Sembiring, Yan, Heroe Soebroto, -, Puruhito, -, Dhihintia Jiwangga Suta Winarno, -, I Gusti Agung Made Adnyanya Putra, -, Sri Pramesthi Wisnu Bowo Negoro, -, Ketut Putu Yasa, -, effrey Jeswant Dillon, -
• Format: Article PeerReviewed
• Language: English; Indonesian; English; English
• Published: Fakultas Kedokteran Unair
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/133154/1/12%20artikel.pdf; https://repository.unair.ac.id/133154/2/karil%2012.pdf; https://repository.unair.ac.id/133154/3/12%20turnitin.pdf; https://repository.unair.ac.id/133154/4/12%20Korespondensi.pdf; https://repository.unair.ac.id/133154/; https://e-journal.unair.ac.id/FMI/article/view/48843; https://doi.org/10.20473/fmi.v59i3.48843
• Institution: Universitas Airlangga

Abstract Portal hypertension is the second most common gastrointestinal bleeding in cirrhosis and non-cirrhosis patients. The splenorenal shunt surgery is a potential intervention that may be considered for portal hypertension patients with clinical symptoms such as upper gastrointestinal bleeding caused by the rupture of gastro-esophageal varices. In this study, the researchers aimed to analyze the efficacy, clinical outcomes, and safety of splenorenal shunt surgery in portal hypertension patients. The sources were obtained from electronic search databases, including PubMed, Google Scholar, and ScienceDirect, using the keywords "Efficacy," "Safety," and "Clinical Outcomes." in relation to splenorenal shunt surgery in portal hypertension patients. The researchers set specific criteria for inclusion and exclusion to select the articles. This systematic review revealed the efficacy of the splenorenal shunt procedure with favorable outcomes. The success rate of splenorenal shunt surgery in reducing the clinical symptoms of portal hypertension varied between 66% and 100%. The prevailing complications observed in this study were shunt thrombosis, rebleeding, and thrombocytopenia. However, notable improvements could be achieved with general treatment. In terms of short- and long-term clinical outcomes, the splenorenal shunt procedure demonstrated favorable results. It can be concluded that splenorenal shunt surgery provides excellent clinical outcomes and should be considered a viable treatment option for patients with both cirrhotic and non-cirrhotic portal hypertension.