Sorbitol Dehydrogenase and Other Liver Enzymes Before and After Five Days Remdesivir Therapy in Covid-19 Patients

• Main Authors: Puspa Wardhani, -, Kustiah, M. Robiul Fuadi, Yulia Nadar Indrasari, Dwita Riadini, Bambang Pujo Semedi, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: 2023
• Subjects: RB37-56.5 Clinical pathology. Laboratory technique
• Online Access: https://repository.unair.ac.id/133341/1/Sorbitol%20Dehydrogenase%20and%20Other.pdf; https://repository.unair.ac.id/133341/2/T-Sorbitol%20Dehydrogenase%20and%20Other.pdf; https://repository.unair.ac.id/133341/3/Sorbitol%20Dehydrogenase%20and%20Other.pdf; https://repository.unair.ac.id/133341/
• Institution: Universitas Airlangga

The antiviral remdesivir has the potential to cause drug-induced liver injury in Covid-19 patients as seen in increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Sorbitol dehydrogenase (SDH) is a cytoplasmic liver enzyme and can increase in acute liver injury, so it has be...