EFEKTIVITAS PROBIOTIK SEBAGAI ANTI-ALERGI PADA MENCIT YANG DISENSITISASI OVALBUMIN

• Main Author: GHEA IKA LARA RATRI
• Format: Theses and Dissertations NonPeerReviewed
• Language: Indonesian
• Published: 2025
• Subjects: RB37-56.5 Clinical pathology. Laboratory technique; SF405.5-407 Laboratory animals
• Online Access: https://repository.unair.ac.id/134978/1/4.%20EFEKTIVITAS%20PROBIOTIK%20SEBAGAI%20ANTI-ALERGI.pdf; https://repository.unair.ac.id/134978/; http://www.lib.unair.ac.id
• Institution: Universitas Airlangga

The purpose of this research was to measure effectivity probiotic for inhibit and decreasing amoWJt of IgE and increasing amoWlt of IgG2a .. l8 male mice age 12-14 weeks was divided into three groups. Each group filled with 6 mice. Group A was given ovalbumin and probiotic Lactobacillus rhamnosus GG (LGG), group B was given ovalbumin and probiotic Lactobacillus plan/arum JS-10506 (LIS), group C was given ovalbumin only. The serum of sample were determined by using ELISA reader at 405 nm. Data were analyzed by MANOVA (Multi Analysis of Variant), if there were any differences, the analyzes will be continued with DWJcan test. The result from this research showed the effectivity differences of probiotic. In decreasing amoWJt of IgE, Lactobacillus rhamnosus GG (LGG) had Optical Density (OD) that not significant (P>0,05) with Lactobacillus plantarum JS-10506 (LIS} and significant (P<0,05} with placebo. At increasing amoWJt ofigG2a, Lactobacillus plantarum JS-10506 (LIS) had Optical Density (OD) that significant (P<0,05} with Lactobacillus rhamnosus GG (LGG) and placebo.