POTENSI BUAH MERAH (Pandanus conoideus) TERHADAP SIKLUS ESTRUS DAN EKSPRESI KASPASE 9 PADA MENCIT (Mus musculus) YANG TERPAPAR TESTOSTERON PROPIONAT
This research aims to demonstrate the potencity of red fruit (Pandanus conoideus) on mice (Mus musculus) exposed by testosterone propionate as observed from estrous cycle and caspase 9 expression. This research uses a laboratory experimental method with completely randomized design. As many as 20...
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| Main Author: | |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian Indonesian |
| Published: |
2016
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/40022/1/1.%20ABSTRAK.pdf http://repository.unair.ac.id/40022/9/323.%2040022-ilovepdf-compressed.pdf http://repository.unair.ac.id/40022/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian Indonesian |
| Summary: | This research aims to demonstrate the potencity of red fruit (Pandanus conoideus)
on mice (Mus musculus) exposed by testosterone propionate as observed from estrous
cycle and caspase 9 expression. This research uses a laboratory experimental method
with completely randomized design. As many as 20 fertile mice were exposed by
testosterone propionate 100mg/kgBW/day via sc for 14 days. 20 mice have been
exposed by testosterone propionate were divided into 4 groups. P0 as control group
without administration of red fruit, P1 treatment group given administration of
100mg/kgBW/day via peroral for 14 days, P2 treatment group given administration of
200/kgBW/day via peroral for 14 days and P3 treatment group given administration of
300/kgBW/day via peroral for 14 days. Swab vagina were collected in the day 5, 10 and
15 administration of red fruit.
The result of estrous cycle in swab vagina day 5 administration of red fruit
showed no significant differences between groups. Swab vagina day 10 and 15
administration of red fruit were significantly difference between groups. The result of
the caspase 9 expression readings showed that P0 were significantly difference than
treatment groups, P1 were significantly difference than others treatment groups and
between P2 and P3 showed no significant difference. Result of this research indicate
that red fruit (Pandanus conoideus) had potency to fixed estrous cycle and decreased
expression of caspase 9 in mice (Mus musculus) exposed by testosterone propionate |
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