PENGARUH KEPOLARAN PELARUT PADA SINTESIS OKTIL 3-HIDROKSISINAMAT DARI BAHAN AWAL ASAM 3-HIDROKSISINAMA T

• Main Author: IKE TERYASTUTIK, 059912118
• Format: Theses and Dissertations NonPeerReviewed
• Language: English
• Published: 2004
• Subjects: RS1-441 Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/56203/1/KK%20FF%2068.04%20Ter%20P%282003%29.pdf; http://repository.unair.ac.id/56203/; http://lib.unair.ac.id
• Institution: Universitas Airlangga

The aim of this research is to compare the effect of polarity of solvent in the synthesis of octyl-3-hydroxycinnamate. The solvent used in this research were tetrahydrofuran (THF) and benzena. Tetrahydrofuran (THF) has dielectric constant 7,58 and dipole moment 1,74, while benzena has dielectric constant 2,28 and dipole moment O. The resulted compound in tetrahydrofuran (THF) was liquid in room temperature and the colour was brownish yellow. It gave 49,43 % yields. The identification of the resulted compound was done by TLC test, refractive index, UV-Vis spectrophotometry, FI/IR spectrophotometry and gas chromatography-mass spectra (GC-MS). There were no resulted compound in benzena. 3-hydroxycinnamic acis as starting material was not solvated in benzena so the ionization can't occur and octyl3-hydroxycinnamate can't be resulted.