Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves

• Main Authors: Achmad, Fuad, Tutik, Sri Wahyuni, Aty, Widyawaruyanti, Maria, Inge Lusida c, Soetjipto, Soetjipto, Hiroyuki, Fuchino, Nobuo, Kawahara, Yoshitake, Hayashi, Chie, Aoki, Hak, Hotta
• Format: Article PeerReviewed
• Language: English; Indonesian
• Published: Elsevier 2014
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/56563/1/1-s2.0-S0367326X14002810-main.pdf__tid%3D7df1301c-241e-11e7-b908-00000aab0f01%26acdnat%3D1492510083_fd72c5f22e04b1acabec918cb84d2c8a; http://repository.unair.ac.id/56563/2/6%20Penilaian%20Reviewer.pdf; http://repository.unair.ac.id/56563/; http://www.sciencedirect.com/science/article/pii/S0367326X14002810
• Institution: Universitas Airlangga

Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70–80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, wh...