Aktivitas antiviral batang Eucalyptus globulus terhadap virus hepatitis C JFH1a

• Main Authors: Achmad, Fuad Hafid, Titania, Puspa Versiati, Aty, Widyawaruyanti
• Format: Article PeerReviewed
• Language: Indonesian; Indonesian; English; English
• Published: Fakultas Farmasi Unair 2014
• Subjects: QR355 Virology; R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; SF780.2-780.7 Veterinary microbiology, bacteriology, virology, mycology
• Online Access: https://repository.unair.ac.id/56619/12/19%20Penilaian%20Reviwear-min.pdf; https://repository.unair.ac.id/56619/13/BUKTI%20C-19%20FUAD-min.pdf; https://repository.unair.ac.id/56619/23/C32-ARTIKEL.pdf; https://repository.unair.ac.id/56619/24/C32-PEER%20REVIEW.pdf; https://repository.unair.ac.id/56619/
• Institution: Universitas Airlangga

In intro antiviral activity of Eucallptus globulus stem against H.patitis C Yinrs hos been done. Previous sludies showed that 8096 ethanol extract tJ Eucallptus globulus stems has potential activity as an anlihepatitis C virus against J6rJFHl ttith lC5s valae cJ 4j.0 pg /ml. The aim .f this study .rrr.s lo determine the anti-hepqtilis C qctiity (f ex.tt'act and fractions tJ Eucal'yptus globulus stems against 2a strain cf JFHIa h.pqtilis irus. The 8094 ethqaol extract and dichloromethane, ethyl acetate. batanol and water fraction were tested for their antiHcy activit!. The resul* showed that the ethanol extrqct .f Eucalytw globulus slems, dichloromethane, ethyl acetate, and butanolfraction haw actiyily in inhibiring the yiral it..fectioa <.f cells with ICso yqlue cf 10.19 pe/nl; 1.64 pg/mL; 10.49 pS/nL; and 18.78 pg/ml reipectively. The 'weter.fraclion was ot acliye with IC j0 value tf 205.79 pg/ml. Phytochemical screening using lhin laler chromatography shown that the actiye fraclions connined cortpounds known qs terpenoids and flavonoids. Further sndies cfcompounds that have anti-hepatitis C actiity qre needed.