Synthesis and Molecular Docking Study of 4-Chlorophenylquinazoline-4-[3h]-One Derivatives as COX-2 Inhibitor

• Main Authors: Tutuk Budiati, Suko Hardjono, Melanny Ika Sulistyowaty
• Format: Article PeerReviewed
• Language: English; English; English; English; English; Indonesian
• Published: International Journal of Pharmaceutical and Clinical Research 2016
• Subjects: RS Pharmacy and materia medica
• Online Access: https://repository.unair.ac.id/59849/1/International%20Journal%20of%20Pharm%20and%20Clin%20Research%20%28cover%291.pdf; https://repository.unair.ac.id/59849/2/IJPCR%2CVol8%2CIssue12%2CArticle9.pdf; https://repository.unair.ac.id/59849/3/Nilai%20IJPCR.pdf; https://repository.unair.ac.id/59849/17/C-10%20Similarity.pdf; https://repository.unair.ac.id/59849/19/C-10%20Artikel.pdf; https://repository.unair.ac.id/59849/22/c10.pdf; https://repository.unair.ac.id/59849/; http://ijpcr.com/volume8issue12/
• Institution: Universitas Airlangga

According to data from the World Health Organization in 2014, cancer was the second biggest cause of death after heart disease. Several attempts have been made to produce the anticancer drug candidate. Modification of molecules against cancer drugs have been done so they became more effective and ef...