EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY

This research aimed to demonstrate the effect of Moringa oleifera leaf extract on the histopathological features of testicular seminiferous tubules of mice (Mus musculus) exposed to methylmercury. Twenty male mice were divided into five groups (C –, C +, T 1, T 2, T 3) and treated for 21 days. C...

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Main Author: ANNISE PROBONINGRAT, 061211132111
Format: Theses and Dissertations NonPeerReviewed
Language:English
English
Published: 2016
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Online Access:http://repository.unair.ac.id/59953/1/ABSTRACT%20KKC%20KK%20KH.%2006.17%20Pro%20e.pdf
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spelling id-langga.599532017-08-07T18:49:22Z http://repository.unair.ac.id/59953/ EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY ANNISE PROBONINGRAT, 061211132111 QL1-991 Zoology QP501-801 Animal biochemistry This research aimed to demonstrate the effect of Moringa oleifera leaf extract on the histopathological features of testicular seminiferous tubules of mice (Mus musculus) exposed to methylmercury. Twenty male mice were divided into five groups (C –, C +, T 1, T 2, T 3) and treated for 21 days. C – were administered 0.01 ml aquadest, C + were administered 0.4 mg/kg bw methylmercury, T 1 were administered 200 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw of methylmercury, T 2 were administered 400 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw methylmercury, and T 3 were administered 800 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw methylmercury. The histopathological features of testicular seminiferous tubules were examined using Modified Johnsen Scoring method. The obtained data were analyzed with Kruskal- Wallis and Mann-Whitney test. The result showed that Moringa oleifera leaf extract reduced the damage of testicular seminiferous tubules of mice (Mus musculus) exposed to methylmercury. The dose of 400 mg/kg bw Moringa oleifera leaf extract gave the best protective effect compared to those of 200 and 800 mg/kg bw. 2016 Thesis NonPeerReviewed text en http://repository.unair.ac.id/59953/1/ABSTRACT%20KKC%20KK%20KH.%2006.17%20Pro%20e.pdf text en http://repository.unair.ac.id/59953/2/FULLTEXT%20KKC%20KK%20KH.%2006.17%20Pro%20e.pdf ANNISE PROBONINGRAT, 061211132111 (2016) EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY. Skripsi thesis, Universitas Airlangga. http://lib.unair.ac.id
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
English
topic QL1-991 Zoology
QP501-801 Animal biochemistry
spellingShingle QL1-991 Zoology
QP501-801 Animal biochemistry
ANNISE PROBONINGRAT, 061211132111
EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
description This research aimed to demonstrate the effect of Moringa oleifera leaf extract on the histopathological features of testicular seminiferous tubules of mice (Mus musculus) exposed to methylmercury. Twenty male mice were divided into five groups (C –, C +, T 1, T 2, T 3) and treated for 21 days. C – were administered 0.01 ml aquadest, C + were administered 0.4 mg/kg bw methylmercury, T 1 were administered 200 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw of methylmercury, T 2 were administered 400 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw methylmercury, and T 3 were administered 800 mg/kg bw Moringa oleifera leaf extract + 0.4 mg/kg bw methylmercury. The histopathological features of testicular seminiferous tubules were examined using Modified Johnsen Scoring method. The obtained data were analyzed with Kruskal- Wallis and Mann-Whitney test. The result showed that Moringa oleifera leaf extract reduced the damage of testicular seminiferous tubules of mice (Mus musculus) exposed to methylmercury. The dose of 400 mg/kg bw Moringa oleifera leaf extract gave the best protective effect compared to those of 200 and 800 mg/kg bw.
format Theses and Dissertations
NonPeerReviewed
author ANNISE PROBONINGRAT, 061211132111
author_facet ANNISE PROBONINGRAT, 061211132111
author_sort ANNISE PROBONINGRAT, 061211132111
title EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
title_short EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
title_full EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
title_fullStr EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
title_full_unstemmed EFFECT OF Moringa oleifera LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF TESTICULAR SEMINIFEROUS TUBULES OF MICE (Mus musculus) EXPOSED TO METHYLMERCURY
title_sort effect of moringa oleifera leaf extract on the histopathological features of testicular seminiferous tubules of mice (mus musculus) exposed to methylmercury
publishDate 2016
url http://repository.unair.ac.id/59953/1/ABSTRACT%20KKC%20KK%20KH.%2006.17%20Pro%20e.pdf
http://repository.unair.ac.id/59953/2/FULLTEXT%20KKC%20KK%20KH.%2006.17%20Pro%20e.pdf
http://repository.unair.ac.id/59953/
http://lib.unair.ac.id
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