POTENSI EKSTRAK DAUN KAMBOJA ( Plumeria acuminata) TERHADAP JUMLAH ANGIOGENESIS DAN SEL PMN PADA LUKA INSISI MENCIT (Mus musculus)

• Main Author: MAZAYA RAMADHANI NADHILA PUTRI, 061011209
• Format: Theses and Dissertations NonPeerReviewed
• Language: English; Indonesian
• Published: 2016
• Subjects: QP501-801 Animal biochemistry; QR180 Immunology
• Online Access: http://repository.unair.ac.id/60429/1/ABSTRACT%20KKC%20KK%20KH.%2075.17%20Put%20p.pdf; http://repository.unair.ac.id/60429/2/FULLTEXT%20KKC%20KK%20KH.%2075.17%20Put%20p.pdf; http://repository.unair.ac.id/60429/; http://lib.unair.ac.id
• Institution: Universitas Airlangga

This research was conducted to verify the potential of Kamboja leaves (Plumeria acuminata), as a medicinal plant for wound healing incision on mice. Twenty of two-three months old male mice with 25 g average body weight was divided into five treatment groups, a negative control (P0) was given CMC Na, positive control (P1) was given Povidone iodine 10%, P2, P3, P4 was given concentration 15%, 20%, 25% of kamboja leaves extract that given topically at two time a day respectively. Data was obtained by microscopic observation of the wound skin, based on semiquantitative data scoring including angiogenesis, and inflammatory cells (PMN). The data were statistically analyzed by Kruskal-Wallis to be continued with Mann-Whitney test. The result showed that there is no were significant different (p<0,05) between treatment groups of inflammatory cells (PMN) and angiogenesis.