POTENSI HEPATOPROTEKTIF PASTA TOMAT (Lycopersicon esculentum) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT (Mus musculus) YANG DIPAPAR BORAKS
The purpose of this research was to evaluate the hepatoprotective potency of tomato paste (Lycopersicon esculentum) against histopathological appereance of mice (Mus musculus) liver exposed to borax. Twenty four mice (Mus musculus) with 60-90 day ages and 20 g avarage of body weight were divided...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English Indonesian |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/60945/1/ABSTRACT%20KKC%20KK%20KH.%20177.17%20Wah%20p.pdf http://repository.unair.ac.id/60945/2/FULLTEXT%20KKC%20KK%20KH.%20177.17%20Wah%20p.pdf http://repository.unair.ac.id/60945/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | English Indonesian |
| Summary: | The purpose of this research was to evaluate the hepatoprotective potency
of tomato paste (Lycopersicon esculentum) against histopathological appereance
of mice (Mus musculus) liver exposed to borax. Twenty four mice (Mus
musculus) with 60-90 day ages and 20 g avarage of body weight were divided
into six groups (P0 , P1, P2, P3, P4, and P5). P0 was treated with sterile aquadest
0,1 ml/20g Bw/day, P1 was treated with borax 7,5 mg/20g Bw/day, P2 was
treated with tomato paste 300mg/20g Bw/day, P3 was treated with tomato paste
150mg/20g Bw/day and borax 7,5 mg/20g Bw/day, P4 was treated with tomato
paste 300mg/20g Bw/day and borax 7,5 mg/20g Bw/day, and P5 was treated with
tomato paste 450mg/20g Bw/day and borax 7,5 mg/20g Bw/day. This research
has been conducted for 14 days. The data of histopatological appereance were
analyzed with Kruskal-Wallis and continued with Man-Whitney. Result showed
there were significant (p<0.05) different between treatment groups. This
research concluded that tomato paste with dose 450mg/20g BB daily can prevent
the damage of hepar that exposed to borax. |
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