MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)

The purpose of this experiment was to know the effect of Mimosa pudica root extract (normal water extraction) on mortality and muscle histopatological in experimental animal (Rattus norvegicus) which injected with LD50 of Naja sputatrix venom. Fresh Mimosa pudica root dried without sunshine and g...

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Main Author: Briantono Willy Rendragraha, 061211132041
Format: Theses and Dissertations NonPeerReviewed
Language:English
Indonesian
Published: 2016
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Online Access:http://repository.unair.ac.id/61171/1/ABSTRACT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf
http://repository.unair.ac.id/61171/2/FULLTEXT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf
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spelling id-langga.611712017-08-30T17:13:32Z http://repository.unair.ac.id/61171/ MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix) Briantono Willy Rendragraha, 061211132041 QL1-991 Zoology QL360-599.82 Invertebrates The purpose of this experiment was to know the effect of Mimosa pudica root extract (normal water extraction) on mortality and muscle histopatological in experimental animal (Rattus norvegicus) which injected with LD50 of Naja sputatrix venom. Fresh Mimosa pudica root dried without sunshine and ground into coarse powder with steamroller (mash 3mm). Plant extract were prepared by stirring 4 g of the powder into 200 ml of water for 3 hours at room temperature and filtered with muslin cloth before freezdried. 30 rat divided into five groups, P0(C+), P1(C-) P2, P3, and P4. P0 (positive control group) injected by saline intra muscular and given aquadest peroral after five minutes, P1 (negative control) injected with Naja sputatrix venom and given aquadest peroral after five minutes. P2, P3, and P4 injected by Naja sputatrix venom and given Mimosa pudica extract with 250mg/KgBW, 500mg/KgBW, and 1000mg/KgBW doses. All of the experimental animal observed about six hours and than euthanized, musculus gluteus maximus (location of injection) was taken for histopatological examination. In this experiment observed that the normal water extraction of mimosa pudica can’t reduce mortality of experimental animals but it can decrease muscle damage in 1000mg/KgBW dose. 2016 Thesis NonPeerReviewed text en http://repository.unair.ac.id/61171/1/ABSTRACT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf text id http://repository.unair.ac.id/61171/2/FULLTEXT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf Briantono Willy Rendragraha, 061211132041 (2016) MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix). Skripsi thesis, Universitas Airlangga. http://lib.unair.ac.id
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
Indonesian
topic QL1-991 Zoology
QL360-599.82 Invertebrates
spellingShingle QL1-991 Zoology
QL360-599.82 Invertebrates
Briantono Willy Rendragraha, 061211132041
MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
description The purpose of this experiment was to know the effect of Mimosa pudica root extract (normal water extraction) on mortality and muscle histopatological in experimental animal (Rattus norvegicus) which injected with LD50 of Naja sputatrix venom. Fresh Mimosa pudica root dried without sunshine and ground into coarse powder with steamroller (mash 3mm). Plant extract were prepared by stirring 4 g of the powder into 200 ml of water for 3 hours at room temperature and filtered with muslin cloth before freezdried. 30 rat divided into five groups, P0(C+), P1(C-) P2, P3, and P4. P0 (positive control group) injected by saline intra muscular and given aquadest peroral after five minutes, P1 (negative control) injected with Naja sputatrix venom and given aquadest peroral after five minutes. P2, P3, and P4 injected by Naja sputatrix venom and given Mimosa pudica extract with 250mg/KgBW, 500mg/KgBW, and 1000mg/KgBW doses. All of the experimental animal observed about six hours and than euthanized, musculus gluteus maximus (location of injection) was taken for histopatological examination. In this experiment observed that the normal water extraction of mimosa pudica can’t reduce mortality of experimental animals but it can decrease muscle damage in 1000mg/KgBW dose.
format Theses and Dissertations
NonPeerReviewed
author Briantono Willy Rendragraha, 061211132041
author_facet Briantono Willy Rendragraha, 061211132041
author_sort Briantono Willy Rendragraha, 061211132041
title MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
title_short MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
title_full MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
title_fullStr MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
title_full_unstemmed MANFAAT EKSTRAK AKAR PUTRIMALU (Mimosa pudica) TERHADAP MORTALITAS DAN GAMBARAN HISTOPATOLOGI OTOT TIKUS (Rattus norvegicus) YANG DIINJEKSI BISA ULAR SENDOK JAWA (Naja sputatrix)
title_sort manfaat ekstrak akar putrimalu (mimosa pudica) terhadap mortalitas dan gambaran histopatologi otot tikus (rattus norvegicus) yang diinjeksi bisa ular sendok jawa (naja sputatrix)
publishDate 2016
url http://repository.unair.ac.id/61171/1/ABSTRACT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf
http://repository.unair.ac.id/61171/2/FULLTEXT%20KKC%20KK%20KH.%20211.17%20Red%20m.pdf
http://repository.unair.ac.id/61171/
http://lib.unair.ac.id
_version_ 1681148245314633728