EFEK PEMBERIAN VITAMIN C DAN E TERHADAP GAMBARAN HISTOPATOLOGI DUODENUM MENCIT YANG DIPAPAR BORAKS
The aim of this research was to investigate the effect of vitamin C and E towards histopathological changes of duodenum in mice induced with borax. Twenty five male mice of BALB/c strain divided into five groups; K1 (vitamin control) was given 0,56 mg/mice /day of vitamin C solution combinated 2,...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian Indonesian |
| Published: |
2016
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/62018/1/KH.264.17%20.%20Ama.e%20-%20ABSTRAK.pdf http://repository.unair.ac.id/62018/2/KH.264.17%20.%20Ama.e%20-%20SEC.pdf http://repository.unair.ac.id/62018/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian Indonesian |
| Summary: | The aim of this research was to investigate the effect of vitamin C and E towards
histopathological changes of duodenum in mice induced with borax. Twenty five
male mice of BALB/c strain divided into five groups; K1 (vitamin control) was
given 0,56 mg/mice /day of vitamin C solution combinated 2,1 mg/mice/day of
vitamin E solution, K2 (borax control) was given 5,2 mg/mice/day of boraks, P1
was given combination of 0,56 mg/mice/day vitamin C and 2,1 mg/mice/day
vitamin E solutions and 5,2 mg/mice/ day of borax, P2 was given combination of
1,12 mg/mice /day of vitamin C and 4,2 mg/mice/day of vitamin E solutions and
5,2 mg/mice/day of borax, P3 was given combination of 2,24 mg/mice/day of
vitamin C and 4,2 mg/mice/day of vitamin E solutions and 5,2 mg/mice/day of
borax. Borax solution on P3, P4 and P5 groups induced in an hour after each
groups treated with combination of vitamin C and E solutions. The treatment were
given by oral gavage for 14 days. The result against submucosal edema of
duodenum indicated there was not any significant difference (P>0.05) between K1
(vitamin control) and K2 (boraks control) groups. There was a signifant difference
between K2 (borax control) with P1 and P3 groups. There was indicated that
combination of vitamin C and vitamin E decrease the submucosal edema of
duodenum induced with borax. The result against the damage of mucous epithelial
indicated there was a significant difference (P<0,05) between K2 group with P1,
P2, and P3 groups. There was not any significant difference between P1, P2, and
P3 groups. There was indicated that combination of vitamin C and vitamin E
decrease the submucosal edema of duodenum induced with boraks. |
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