Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR,...
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| Main Authors: | , |
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| Format: | Article PeerReviewed |
| Language: | English English English |
| Published: |
Scholars Research Library
2015
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/63039/1/Cover.pdf http://repository.unair.ac.id/63039/2/Bukti%20C09.%20Phenolic%20compounds%20from%20the%20stem%20bark%20of%20Erythrina%20..........pdf http://repository.unair.ac.id/63039/3/Bukti%20C09%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf http://repository.unair.ac.id/63039/ http://www.derpharmachemica.com/ |
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| Institution: | Universitas Airlangga |
| Language: | English English English |
| Summary: | Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl
licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR, HRESIMS, 1D and 2D NMR data. Compounds 1–5 were evaluated for their cytotoxic properties against P-388 cells, their IC values 2.55, 2.43,17.98, 4.31, and 5.82 µg/mL, respectively. Compounds 1, and 5 exhibited very high antioxidant activity against
DPPH radical scavenging. |
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