KARAKTERISTIK FISIK MIKROPARTIKEL Lactobacillus casei DENGAN MATRIKS KOPOLIMER ASAM METAKRILAT TIPE L PADA KADAR 0,5% DAN 1,0% (Metode Spray Drying Suhu Inlet 110 ᵒC)
Probiotics are living organisms that provide health benefits such as improving normal flora balance and have immunomodulatory effects when consumed in sufficient quantities by the host (ie, human or ani mal). A special delivery system is needed to protect probiotics in their target of action, na...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian Indonesian |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/65407/1/FF.F.%2008-17%20Sho%20k%20abstrak.pdf http://repository.unair.ac.id/65407/2/FF.F.%2008-17%20Sho%20k%20fulltext.pdf http://repository.unair.ac.id/65407/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian Indonesian |
| Summary: | Probiotics are living organisms that provide health benefits such as
improving normal flora balance and have immunomodulatory effects when
consumed in sufficient quantities by the host (ie, human or ani mal). A special
delivery system is needed to protect probiotics in their target of action,
namely intestine. One of the delivery system is microparticle trapping which
can protect the probiotics from extreme environments in the stomach. The
objective of this study was to discover the effect of methacrylic acid
copolymer L type content (0,5% and 1,0%) to physical characteristic of
Lactobacillus casei microparticles made by spray dry method. The matrix
used was methacrylic acid copolymer L type with various concentration in
the formula I and II, 0.5% and 1.0% respectively. The observations on the
physical characteristics of the microparticles were performed in both
formulas. The particle size of formulas I and II was 3.65 μm and 4.07 μm.
The increasing levels of formula I to II decreased the moisture content from
9.56% to 7.34%. It could be seen that the higher content was, the smoother
surface of the microparticle had become. In addition, there was basin on the
surface, not porous and had more spherical form. The FTIR spectra results
indicated that there was more significant reduction of -OH and C=O groups
in formula I to II than the uptake of -OH band and C=O band in methacrylic
acid copolymer L type. Thus, it showed that the hydrogen bonds had been
formed on Lactobacillus casei microparticles. |
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