STUDI PENGGUNAAN DIURETIKA PADA PASIEN SIROSIS HEPATIK DENGAN ASITES (Penelitian Dilakukan di Instalasi Rawat Inap Departemen Ilmu Penyakit Dalam Rumah Sakit Universitas Airlangga Surabaya)
Ascites is the accumulation of fluid in the peritoneal cavity and one of the first decompensation signs of liver disorder. Ascites is one of the complications happened by patients with hepatic cirrhosis. The usual therapy used for ascites is diuretics, along with salt restrictions in the diet. S...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian Indonesian |
| Published: |
2017
|
| Subjects: | |
| Online Access: | http://repository.unair.ac.id/65448/1/FF%20FK%2046-17%20Roh%20s%20Abstrak.pdf http://repository.unair.ac.id/65448/2/FF%20FK%2046-17%20Roh%20s%20Sec.pdf http://repository.unair.ac.id/65448/ http://lib.unair.ac.id |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universitas Airlangga |
| Language: | Indonesian Indonesian |
| Summary: | Ascites is the accumulation of fluid in the peritoneal cavity and
one of the first decompensation signs of liver disorder. Ascites is one of
the complications happened by patients with hepatic cirrhosis. The usual
therapy used for ascites is diuretics, along with salt restrictions in the diet.
Spironolactone and furosemide are the main pharmacological therapy for
ascites.
This study aims to examine the patients characteristic with hepatic
cirrhosis, to examine utilization of diuretic drug using during
hospitalization, and to identify the possibility of Drug Related Problem
(DRP) on diuretic therapy for SH patients with ascites at Airlangga
University Hospital (RSUA) Surabaya. Data was collected with time
limited sampling method in the periode January 1, 2013 until March 31,
2017 Inpatient Instalation in RSUA and has been approve by ethics
committee.
The results on 45 patients that classificated in this study showed
the most common characteristics of patients were males (53.33%), age
45-64 (75.56%), the highest complication with Hypoalbumin (26.67%)
and 6-10 days as the longest treatment (46.67%). Diuretic profiles therapy
were used furosemide (17.78%) and spironolactone (2.22%) as
monotherapy, and also spironolactone and furosemide as combination
therapy (80.00%). Furosemide was the most used in IV especially with
20mg/days (57.78%), while spironolactone was the most used in PO
especially with 100mg/days (44.44%). DRP that occurs is a potential drug
interaction on the use of spironolactone with potassium (24.44%). |
|---|