UJI AKTIVITAS ANTIMALARIA EKSTRAK ETANOL DAUN MENGKUDU (Morinda citrifolia) TERHADAP PLASMODIUM FALCIPARUM IN VITRO
Malaria remains one of worldwide concerns with over 200 millions of new cases and more than 400.000 deaths in 2015. Drug resistance has been frequently reported in many regions all around the world. Those reports suggest that there is still an alternative needed for Malaria’s medication, preferab...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English Indonesian |
| Published: |
2017
|
| Subjects: | |
| Online Access: | http://repository.unair.ac.id/68520/1/FK%20PD%20376-17%20Ulw%20u%20Abstrak.pdf http://repository.unair.ac.id/68520/2/FK%20PD%20376-17%20Ulw%20u%20Sec.pdf http://repository.unair.ac.id/68520/ http://lib.unair.ac.id |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universitas Airlangga |
| Language: | English Indonesian |
| Summary: | Malaria remains one of worldwide concerns with over 200 millions of new cases
and more than 400.000 deaths in 2015. Drug resistance has been frequently reported
in many regions all around the world. Those reports suggest that there is still an
alternative needed for Malaria’s medication, preferably from natural origin. Noni
(Morinda citrifolia) is a plant which is familiar in Indonesia. It has antioxidant,
antifungal, antiinflamation, analgetic, and antiviral activities. This study aims to
evaluate the in vitro antimalarial activity of ethanolic extract of Morinda citrifolia
leaves. The extract was obtained by multiple maceration of M. citrifolia leaves with
70% etanol as its solutant. The in vitro assay was done using 3D7 strain of
Plasmodium falciparum with consentration of extracts were 100; 10; 1; 0,1; and
0,01 μg/mL. Antimalaria activity result on noni’s leaves was calcutated using probit
analysis and showed the value of IC50 22,68 μg/mL which can be concluded as
active in antimalaria. |
|---|