TOLERAN PADA MENCIT NEONATUS BALB/c SETELAH PAPARAN ALERGEN PADA INDUK BUNTING (Kajian toleran terhadap ekspresi sitokin IL-2, IFN-
Background : Allergy is a health problem that increasingly need attention. Prevention efforts still have not managed to improve the disease satisfactorily. Meanwhile in–utero prevention efforts based on immunologies comprehension remains unclear. Research on tolerance in newborn Balb/c mice after...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | http://repository.unair.ac.id/71200/1/abstrak.pdf http://repository.unair.ac.id/71200/2/full%20text.pdf http://repository.unair.ac.id/71200/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universitas Airlangga |
| Language: | English English |
| Summary: | Background : Allergy is a health problem that increasingly need attention. Prevention
efforts still have not managed to improve the disease satisfactorily. Meanwhile in–utero
prevention efforts based on immunologies comprehension remains unclear. Research on
tolerance in newborn Balb/c mice after exposing with allergens on pregnant mice needs
to be done.
Aims : To explain the allergens exposure on pregnant Balb/c mice and its role to
tolerance in newborn mice by measuring cytokines Th1, Th2, Treg and IgG-1, IgG-2a,
IgG-2b, IgG3 subclass level and IgM, IgA, IgE.
Methods : Research in Virology & Immunology Laboratory, Dept of Microbiology
Veterinary Faculty Airlangga University. Experimental study post-test only control
group design, using factorial design to asses the effect of allergens Mite, Cat Hair, Dog
Hair, Chicken Albumin and Cow Milk Protein with low-dose and high dose on pregnant
Balb/c and newborn mice to tested variables. Sixty Balb/c pregnant mices divided into
intervention
group and control. Blood sampling of pregnant Balb/c and newborn mice to assess
Th1(IL-2, IFN- |
|---|