INFLUENCE OF POMEGRANATE EXTRACT (Punica granatum L.) ON IMPROVEMENT OF PERCENTAGE OF SPERMATOZOA CAPACITATION AND ACROSOME REACTION OF WHITE RAT (Rattus norvegicus)
The aim of this research is to know the effect of pomegranate (Punica granatum L.) on the improvement of spermatozoa quality that is increase of percentage of capacitation and acrosome reaction in white rat (Rattus norvegicus). This research used 20 healthy white rat (Rattus norvegicus) with aver...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/71617/1/KH.%2078-18%20Sat%20i%20Abstrak.pdf http://repository.unair.ac.id/71617/2/KH.%2078-18%20Sat%20i.pdf http://repository.unair.ac.id/71617/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | English English |
| Summary: | The aim of this research is to know the effect of pomegranate (Punica
granatum L.) on the improvement of spermatozoa quality that is increase of
percentage of capacitation and acrosome reaction in white rat (Rattus norvegicus).
This research used 20 healthy white rat (Rattus norvegicus) with average age 2-3
months old, 200-300 g. Research design using completely randomized design
(CRD) with four treatments and 5 replications. Rats were randomly divided into 4
treatment groups. Rat in the negative control group not treated just kept alone,
solvent control group were given CMC Na 0,5% and is exposed to heat, the
treatment groups 1, 2, and 3 induced pomegranate extract standardized to 40%
ellagic acid at a dose of 75mg / kg, 150mg / kg and 300mg /kg perorally with
doses 1 ml/rat/day gastric for along 14 days and exposed to heat. Data were
analyzed using One Way Analysis of Variant (ANOVA) followed by Duncan
(p<0,05). The result showed that there was significant effect from therapy on the
quality of rats spermatozoa especially to capacitation and acrosome reaction. The
treatment from treatment 2 group showed the best result in maintaining the quality
of rats spermatozoa with 27.6± 3.04 values for capacitation and 6,80 ± 1,30 for
acrosome reactions. Extract of pomegranate (Punica granatum L.) standardized to
40% ellagic acid has a significant change in improve the quality of spermatozoa,
namely an increase in the percentage of capacitation and acrosome reactions in
white rats (Rattus norvegicus) exposed to heat. |
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