Improvement of Dissolution Properties Through Acyclovir-Succinic Acid Cocrystal Using Solvent Evaporation Technique.

• Main Authors: Hilya Nur Imtihani, Agnes Nuniek Winantari, Dwi Setyawan, Esti Hendradi
• Format: Article PeerReviewed
• Language: English; English; English; English; English; English
• Published: International Journal of Drug Delivery Technology 2017
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/73329/1/C-8%20Artikel.pdf; http://repository.unair.ac.id/73329/14/C-2%20fixed.pdf; http://repository.unair.ac.id/73329/2/C-8%20Validasi%20dan%20Peer%20Reviewer.pdf; http://repository.unair.ac.id/73329/16/C-02%20Reviewer.pdf; http://repository.unair.ac.id/73329/13/Result%20Bukti%20C-02.pdf; http://repository.unair.ac.id/73329/17/C-03%20klarifikasi.pdf; http://repository.unair.ac.id/73329/; http://impactfactor.org/PDF/IJDDT/7/IJDDT,Vol7,Issue4,Article8.pdf
• Institution: Universitas Airlangga

The objective of this research was to prepared acyclovir cocrystals with succinic acid as coformer using three different solvents (ethanol, acetic acid glacial, and 0.1N HCl) to influence the characters and improve the dissolution rate of acyclovir. Cocrystallization of acyclovir with succinic acid...