Solubility, Dissolution Test and Antimalarial Activity of Artesunate Nicotinamide Co-Crystal Prepared by Solvent Evaporation and Slurry Methods

• Main Authors: Dwi Setyawan, Narendra Kusuma, Retno Sari
• Format: Article PeerReviewed
• Language: English; English; English; English; English
• Published: Asian Journal of Pharmaceutical and Clinical Research 2015
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/73333/11/C-08.pdf; http://repository.unair.ac.id/73333/2/C-12%20Validasi%20dan%20Peer%20Reviewer.pdf; http://repository.unair.ac.id/73333/13/C-08%20Result.pdf; http://repository.unair.ac.id/73333/16/Rev%20Similarity%20C-08.pdf; http://repository.unair.ac.id/73333/17/Revisi%20Validasi%20dan%20Penilaian%20Reviewer%20C-08.pdf; http://repository.unair.ac.id/73333/; https://innovareacademics.in/journals/index.php/ajpcr/article/view/4332
• Institution: Universitas Airlangga

Objective: The aims of this study was to investigate the solubility, dissolution rate and antimalarial activity against Plasmodium berghei of artesunate (AR)-nicotinamide co-crystal prepared by solvent evaporation (CoSE) and slurry (CoS) method. Methods: Co-crystals of AR-nicotinamide prepared by s...