STUDI PENGGUNAAN CEFAZOLIN PADA PASIEN FRAKTUR TERBUKA GRADE I (Penelitian dilakukan pada kasus orthopedi di Unit Rekam Medis Rumah Sakit Universitas Airlangga Surabaya)
BACKGROUND. Open fracture infection cases 70% were caused by Gram positive microorganism such as Staphylococcus aureus and Staphylococcus epidermidis. Cefazolin have several benefit such as more active for Gram positive microorganism and due to their high lipofilicity cefazolin has excellent dis...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian Indonesian |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/76933/1/FF.FK.%2027-18%20Sar%20s%20Abstrak.pdf http://repository.unair.ac.id/76933/2/FF.FK.%2027-18%20Sar%20s.pdf http://repository.unair.ac.id/76933/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian Indonesian |
| Summary: | BACKGROUND. Open fracture infection cases 70% were caused by Gram
positive microorganism such as Staphylococcus aureus and Staphylococcus
epidermidis. Cefazolin have several benefit such as more active for Gram
positive microorganism and due to their high lipofilicity cefazolin has
excellent distribution profile in bone.
OBJECTIVES. The aimed of this study was to analyze utilization pattern,
dosage, frequency, timing of administration, and duration usage of cefazolin.
METHODS. The observasional and retrospective method with time limited
sampling from January 2nd, 2014 until December 31st, 2017 and descriptive
analysis was conducted in this study (N=25).
RESULT AND CONCLUTION. The result showed that were 25 patient
with open fracture grade I used cefazolin (1x2g) iv as prophylaxis and
cefazolin (3x1g) iv used as switch. Two pattern of switch 43% used cefazolin
(1x2g) iv and followed by used cefazolin (3x1g) iv. Three Pattern of switch
majority (38%) used cefazolin (1x2g) iv followed by used cefazolin (3x1g)
iv and when patient discharge the hospital received cefadroxil (2x100mg) po.
Four pattern of switch majority (86%) used cefazolin (3x1g) iv followed by
using cefazolin (1x2g) iv and then cefazolin (3x1g) and cefadroxil (2x500mg)
po when discharge the hospital. Timing of administration prophylactic
antibiotic majority 28% received 20 minutes before incision. The duration
usage of cefazolin commonly 44% given 2 days. Based on the description,
pattern usage of cefazolin including dosage, frequency, timing of
administration, and duration usage in open fracture grade I patient at KSM
Orthopaedic Universitas Airlangga Hospital has been appropriate with
guidelines and other references recommendation. |
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