EFFECT OF JUWET (Syzygium cumini) LEAVES EXTRACT AS ADJUVANT THERAPY ON THE KIDNEY HISTOPATHOLOGICAL CHANGES OF MICE (Mus musculus) INFECTED BY Plasmodium berghei
This research aims to understand the effect of juwet (Syzygium cumini) leaves extract as adjuvant treatment in kidney histopathological changes such as, tubular necrosis, glomerulonephritis, interstitial nephritis in mice (Mus musculus) infected by Plasmodium berghei. Twenty five mouses are divid...
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| Main Author: | |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/81443/1/abstrak.pdf http://repository.unair.ac.id/81443/2/full%20text.pdf http://repository.unair.ac.id/81443/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | English English |
| Summary: | This research aims to understand the effect of juwet (Syzygium cumini)
leaves extract as adjuvant treatment in kidney histopathological changes such as,
tubular necrosis, glomerulonephritis, interstitial nephritis in mice (Mus musculus)
infected by Plasmodium berghei. Twenty five mouses are divided into five mices
for 5 groups which are K0 without infection and treatment, K1 infected by
Plasmodium berghei without treatment, K2 infected by Plasmodium berghei with
chloroquine P1 infected by Plasmodium berghei with juwet (Syzygium cumini)
leaves extract and P2 infected by Plasmodium berghei with chloroquine and juwet
(Syzygium cumini) leaves extract as adjuvant therapy. The data is analyzed by
using Kruskal Wallis Test continued by using Mann-Whitney U Test. The result
showed significant differences (P<0,05) on tubular necrosis, glomerulonephritis,
interstitial nephritis of group K1 and K0, K2, P1, P2 but there is no significant
differences (P>0,05) on tubular necrosis, glomerulonephritis, interstitial nephritis
of group K2, P1, and P2. There is significant difference (P<0,05) on tubular
necrosis, glomerulonephritis, interstitial nephritis on K0 and K2, P1, P2. The
result of this research conclude that juwet (Syzygium cumini) leaves extract as
adjuvant therapy able to reduce the damage on kidney histopathological changes
of mice (mus musculus) infected by Plasmdoium berghei |
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