Pengaruh Pemberian Ekstrak spirulina platensis terhadap kadar SGOT dan SGPT pada tikus putih (Rattus noevegicus) yang diinduksi etanol

• Main Authors: Budi, Rendy Setiawan, Wahjuni, Retno Sri, Hidanah, Sri
• Format: Article PeerReviewed
• Language: Indonesian; Indonesian
• Published: Depart. Kedokteran Dasar FKH Unair 2016
• Subjects: SF811-909 Veterinary medicine of special organs, regions, and systems
• Online Access: http://repository.unair.ac.id/83231/1/Bukti%20C26%20Pengaruh%20Pemberian%20Ekstrak%20Spirulina%20.....pdf; http://repository.unair.ac.id/83231/2/Peer%20Review%20Bukti%2026.pdf; http://repository.unair.ac.id/83231/; http://journal.unair.ac.id/JBMV@the-effect-of-spirulina-platensis-extract-to-sgot-and-sgpt-level-article-11593-media-122-category-5.html
• Institution: Universitas Airlangga

The purpose of this study was to determine the effect of Spiru lina platensìs extract to decrease the levels óf SCOT and PT in Wistar rats induced ehandl. Twenty male rats were divided into five groups containing four rats each. They were two control groups and three treatment groups, which was given 200,400, and 800 mJkg BW of Spirulina platensis extract orally. For the first seven days each group was given ethanol 50% 2 ml/kg BW except for control groups. On the 8th day, the treatment of ethanol was stopped and then continued with the giving of Spirulina platensis extract for the treatment groups and CMC Na 1 % solution for control groups for the total of 14 days. Samples were taken at day fl. Then,, the data was compared using ANC)VA test and duncans multiple range test. from the statistical test showed that the extract s pl ru lina platensis show significant difference (P<O,05) towards decrease levels of SGOT and SGPT. On with significant test duncan’s multiple range test SCOT obtained K- not significantly different from Pl, but K- significantly different K +, P2 and P3. SGPT obtained K- not significantly different from K+, P1, P2 and P3 but Pl significantly different P2 and P3 based on the research results can be concluded the effect of S pi ruTina platensis could reduce the levels of SCOT but has not been able to reduce the levels of SGPT white rats (Rattus nortegicus) induced by ethanol Key words : Spirzilina platensis, ethanol, SGOT, SGPT