POTENSI MADU LEBAH Apis dorsata DALAM MENINGKATKAN OSTEOBLAS DAN MENURUNKAN OSTEOKLAS TULANG VERTEBRAE LUMBALIS TIKUS PUTIH (Rattus norvegicus) OVARIOHISTEREKTOMI
The aim of this research was to compare the effect of Apis dorsata honey based on total number of osteoblast and osteoclast cell on ovariohysterectomized rat (Rattus norvegicus). The sample used 60 female rats adapted for 7 days in cluster cage and divide randomly into 5 groups of treatment with...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English Indonesian Indonesian Indonesian |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/83985/1/KH%2072-19%20Ibr%20p-%20-%20ABSTRAK.pdf http://repository.unair.ac.id/83985/2/KH%2072-19%20Ibr%20p-%20-%20DAFTAR%20ISI.pdf http://repository.unair.ac.id/83985/3/KH%2072-19%20Ibr%20p-%20-%20DAFTAR%20PUSTAKA.pdf http://repository.unair.ac.id/83985/4/KH%2072-19%20Ibr%20p-FULLTEXT.pdf http://repository.unair.ac.id/83985/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | English Indonesian Indonesian Indonesian |
| Summary: | The aim of this research was to compare the effect of Apis dorsata honey
based on total number of osteoblast and osteoclast cell on ovariohysterectomized
rat (Rattus norvegicus). The sample used 60 female rats adapted for 7 days in
cluster cage and divide randomly into 5 groups of treatment with 3 times of
repetition (SO, OH, M1, M2, M3). SO was a sham-operated group which the rats
were non ovariohysterectomized and received aquadest. OH was an
ovariohysterectomized group which the rats were ovariohysterectomized and
received aquadest. M1 (1g/kg BW), M2 (2g/kg BW) and M3 (4g/kg BW) was
ovaryohysterectomized groups which the rats were ovaryohysterectomized and
received honey solution of Apis dorsata. The Honey was diluted in 1.5 ml
aquadest and given orally for 1st, 2nd and 3rd months. At 1st, 2nd, and 3rd months the
rats were euthanized and th 5th of lumbar vertebrae was taken with necroption
technique. Osteoblast and osteoclast cell were calculated using optilab
microscope. The result showed the total number of osteoblast and osteoclast cells
was significantly different (p<0.05) between OH group and all the group. The
lowest was on OH group at every 1st, 2nd, and 3rd months of observation. The
result of the lowest osteoclast number is on M2 group and highest on OH group. |
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