Inhibition Of The Mitogen Activated Protein Kinase (MAPK) In The Inflammatory Pain Like State Using SB 203580 and PD 98059 In Mice

• Main Authors: Bambang Subakti Zulkarnain, Kirwanto, Yulistiani, Junaidi Khotib
• Format: Article PeerReviewed
• Language: English; English
• Published: Universitas Airlangga 2010
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/85004/2/C17.pdf; http://repository.unair.ac.id/85004/1/Validasi%20C-17.pdf; http://repository.unair.ac.id/85004/; http://journal.unair.ac.id/download-fullpapers-06%2010008%20BambangSE%20-%20format%20FMI.pdf
• Institution: Universitas Airlangga

The therapeutic management of pain related inflammation is difficult to handle. The inflammatory process is mediated through the mitogen-activated protein kinase (MAPK) signal transduction pathway. Inhibition of this signal with specific inhibitors of p38 and Erk 1/2 MAPK pathway i.e. SB 203580 an...