Potential of Green Chili Extract (Capsicum Annuum) On Myeloma Cells Death

• Main Authors: Rochmah Kurnijasanti, -, Alifvia Izza Putri Edward, -, Yonas Kristijanto, -, Doohan Mahendra, -, Nadya Ivanora Hermanda, -
• Format: Book Section PeerReviewed
• Language: English; English; English
• Published: Atlantis Press 2017
• Subjects: SF600-1100 Veterinary medicine; SF811-909 Veterinary medicine of special organs, regions, and systems
• Online Access: https://repository.unair.ac.id/86207/2/Bukti%20C%2031%20Potential%20of%20Green%20Chili%20...-min.pdf; https://repository.unair.ac.id/86207/6/Peer%20Review%20Potential%20of%20Green%20Chili%20Extract.pdf; https://repository.unair.ac.id/86207/4/Potential%20of%20Green%20Chili%20Extract%20%28Capsicum%20annuum%29%20on%20...pdf; https://repository.unair.ac.id/86207/
• Institution: Universitas Airlangga

The purpose of the study was to determine the potential of the ethanol extract of green chili (Capsicum annum) against the proliferation of myeloma cells. The study used ethanol extract of green chili (Capsicum annum) by maceration. The Myeloma cell concentration was 1.10 -5 ml-1 of medium DMEM and 10% FBS. The treatment of Myeloma cells were divided into 8 treatments with 5 repetitions. The treatment group was treated with the extract of green chili concentration of 1%, 2%, 4%, 8%, 16%, 32%, and 64% by administration of 0.1 ml each microplate, while the control group was treated without the extract of green chili but using aqua pro injection of a placebo substance. Once it is stored into a cooler with CO2 because myeloma cells require CO2 to live, and its growth was observed for 3 days. Observations were made in three days post treatment using miscroscope by observing myeloma living cells, lysis, and dead cells after the addition of extracts of green chili. Data were analyzed descriptively. The results showed that green chili extract concentration could inhibit proliferation of myeloma cells. In the treatment granting extract of green chili of 64% concentration caused 100% myeloma cells die Keywords: Extract, Green chili, Capsicum annum, Proliferation, Myeloma cells death