The Influence of Olive Oil Addition on Increasing Arbutin Penetration in the Carbomer 940 Gel (Observation on Inhibition of Enzym Tyrosinase Activity)

• Main Authors: Widji Soeratri, Tristiana Erawati, Noorma Rosita, Fahriyatul Wahyuni
• Other Authors: Pudjono
• Format: Book Section PeerReviewed
• Language: English; English; English; English; English; English; English; English; English
• Published: Faculty of Pharmacy Universitas Gadjah Mada 2009
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/88571/2/Atikel%20C-21.pdf; http://repository.unair.ac.id/88571/1/C-21%20Result%20-%20The%20Influence%20of%20Olive%20Oil%20Addition%20on%20Increasing%20of%20Arbutin%20Penetration%20in%20the%20Carbomer-940%E2%80%99s%20Gel%20%28Observation%20on%20Inhibition%20of%20Enzyme%20Tyrosinase%20Activity%29%20%281%29.pdf; http://repository.unair.ac.id/88571/5/C-21%20Reviewer.pdf; http://repository.unair.ac.id/88571/6/C-28%20Artikel1.pdf; http://repository.unair.ac.id/88571/7/C-28%20Result.pdf; http://repository.unair.ac.id/88571/8/C-28%20Reviewer.pdf; http://repository.unair.ac.id/88571/10/Artikel%20C-30.pdf; http://repository.unair.ac.id/88571/14/C-30%20Result%20New%20edit.pdf; http://repository.unair.ac.id/88571/15/Validasi%20C-30%20rev.pdf; http://repository.unair.ac.id/88571/
• Institution: Universitas Airlangga

The aim of this study was to investigate the influence of olive oil addition on the increasing of arbutin penetrations in the Carbomer-940's gel; it was observed on inhibition of enzyme tyrosinase activity. High hydrophilicity of arbutin (log P value, -1.35) makes it difficult to permeate throu...