PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum) TERHADAP HISTOPATOLOGI PULMO MENCIT (Mus musculus) YANG DIINFEKSI Mycobacterium tuberculosis
This research aimed to know the effect of clove leaf extract (Syzygium aromaticum) on the histopathology of pulmonary mice(Mus musculus) infected with Mycobacterium tuberculosis. 20 male mice were grouped into 5 groups and given with different treatments. the negative control group was not infect...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English English English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/89229/1/abstrak.pdf http://repository.unair.ac.id/89229/2/daftar%20isi.pdf http://repository.unair.ac.id/89229/3/daftar%20pustaka.pdf http://repository.unair.ac.id/89229/4/full%20text.pdf http://repository.unair.ac.id/89229/ |
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| Institution: | Universitas Airlangga |
| Language: | English English English English |
| Summary: | This research aimed to know the effect of clove leaf extract (Syzygium
aromaticum) on the histopathology of pulmonary mice(Mus musculus) infected
with Mycobacterium tuberculosis. 20 male mice were grouped into 5 groups and
given with different treatments. the negative control group was not infected but on
day 29 to day 56 was given CMC Na 1% solution. The positive control group was
infected with Mycobacterium tuberculosis and day 29 to day 56 was given CMC
Na 1% solution. Group P1, P2, P3 were infected with Mycobacterium
tuberculosis. After that, groups P1, P2, P3 were treated with clove leaf extract
(Syzygium aromaticum) with each dose of 375 mg/KgBB for P1, 750 mg/KgBB
for P2, and 1500 mg/KgBB for P3 on day 29 to day 56. Observation of samples
using microscopic examination with microscope 100x magnification and optilab
viewer. Data analysis using the Kruskal Wallis test and continued by the Mann
Whitney test using the SPSS version 21 program for Windows. The results
showed that clove leaf extract (Syzygium aromaticum) dose 375 mg/ KgBB was
the lowest accumulation of inflammatory scores that approached the negative
control group, so that was effective as an anti-inflammatory due to tuberculosis |
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