OPTIMASI FORMULA MASKER EMULGEL PEEL OFF VCO KOPYOR (Cocos nucifera L.) DENGAN BASIS POLIVINIL ALKOHOL SEBAGAI SEDIAAN ANTIJERAWAT TERHADAP Propionibacterium acnes
Virgin Coconut Oil of Kopyor contained lauric acid that already known has an antibacterial activity against Propionibacterium acnes that ususally improve the severe of pimple. Researches based on the extract virgin coconut oil activity as a natural antimicrobial have been reported. The extract s...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English English Indonesian |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/90651/1/FF.F.20-19%20Sha%20o%20abstrak.pdf http://repository.unair.ac.id/90651/2/FF.F.20-19%20Sha%20o%20daftar%20isi.pdf http://repository.unair.ac.id/90651/3/FF.F.20-19%20Sha%20o%20daftar%20pustaka.pdf http://repository.unair.ac.id/90651/4/FF.F.20-19%20Sha%20o.pdf http://repository.unair.ac.id/90651/ http://lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | English English English Indonesian |
| Summary: | Virgin Coconut Oil of Kopyor contained lauric acid that already
known has an antibacterial activity against Propionibacterium acnes that
ususally improve the severe of pimple. Researches based on the extract
virgin coconut oil activity as a natural antimicrobial have been reported.
The extract solutions were tested for antibacterial activity against
Propionibacterium acnes ATCC 11827 in Nutrient agar. Growth
inhibition test was carried out by agar disk diffusion. The minimum
inhibition concentration (MIC) of the VCO was 20%. In this research,
VCO 20% and 30% was formulated as a component of emulgel peel off
mask containing PVA in various concentration (8% and 10%). The
emulgel peel off mask of VCO kopyor then undergoes viscosity, pH,
drying time, spreadability, droplet size, droplet size distribution, zeta
potential, antibacterial activity, and also stability thermal cycling
evaluation on the temperature 40°±2°C and 4°C±2°C in 3 cycle. Through
this evaluation, the chosen formula was formula 1 containing 20% of
VCO and 8% of PVA. This formula has pH that suitable with skin pH
4,5-6,5 , has no significant difference in zeta potential, good spreadability,
and also undergoes the antibacterial activity determination that has no
signficancy different with the other formula that contains more
concentration of VCO and PVA. |
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