VALIDASI METODE SPEKTROFOTOMETRI UV UNTUK PENETAPAN KADAR NISTATIN DALAM SEDIAAN OVULA
Determination of nystatin in ovule was important to ensure the safety and efficacy of nystatin that used for local candidal infection. The aim of the present study was to obtain a valid UV spectrophotometry method for determination of nystatin in ovule preparation. The maximum wavelength of nyst...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English English Indonesian |
| Published: |
2019
|
| Subjects: | |
| Online Access: | http://repository.unair.ac.id/90873/1/FF.KF.23-19%20Nao%20v%20abstrak.pdf http://repository.unair.ac.id/90873/2/FF.KF.23-19%20Nao%20v%20daftar%20isi.pdf http://repository.unair.ac.id/90873/3/FF.KF.23-19%20Nao%20v%20daftar%20pustaka.pdf http://repository.unair.ac.id/90873/4/FF.KF.23-19%20Nao%20v.pdf http://repository.unair.ac.id/90873/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universitas Airlangga |
| Language: | English English English Indonesian |
| Summary: | Determination of nystatin in ovule was important to ensure the
safety and efficacy of nystatin that used for local candidal infection. The
aim of the present study was to obtain a valid UV spectrophotometry
method for determination of nystatin in ovule preparation. The maximum
wavelength of nystatin was found to be 306 nm. The responses of nystatin
were linear with concentration in the range of 4.980 – 11.951 ppm with a
correlation coefficient (r) value of 0.9991 and Vxo of 1.71%. The accuracy of
the method was calculated as % recovery. The mean of recovery in the
concentration of 80%, 100%, and 120% was 99.80%; whilst the precision
calculated as the relative standard deviation (RSD) was 1.01%. The method
showed good results and fulfill the validation requirements. |
|---|