Molecular Docking of N-benzoyl-N’-(4-fluorophenyl) thiourea Derivatives as Anticancer Drug Candidate and Their ADMET prediction

• Main Authors: Suko Hardjono, Tri Widiandani, Bambang Tri Purwanto, Anindi L. Anindi
• Format: Article PeerReviewed
• Language: English; English; English
• Published: A and V Publication 2019
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/93653/3/C-02%20Artikel.pdf; http://repository.unair.ac.id/93653/1/C-02%20Reviewer.pdf; http://repository.unair.ac.id/93653/2/C-02%20Result.pdf; http://repository.unair.ac.id/93653/; https://www.indianjournals.com/ijor.aspx?target=ijor:rjpt&volume=12&issue=5&article=018
• Institution: Universitas Airlangga

The pharmacophore group found in N-benzoyl-N’-(4-fluorophenyl) thiourea is the same as the urea derivative which has anti-cancer activity, such as hydroxyurea. Because of the presence of these pharmacophore groups, this compound is worthy of being used as parent compound for further development thro...