Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis
Objective: To evaluate the prognostic value of presepsin and procalcitonin in patient with urosepsis. Material & Method: This is an observational prospective study. Patients who fulfilled the criteria for urosepsis at Soetomo Hospital Surabaya were enrolled. Presepsin and procalcitonin were meas...
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The Indonesian Urological Association
2018
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Online Access: | http://repository.unair.ac.id/95453/1/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis_compressed.pdf http://repository.unair.ac.id/95453/2/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis.pdf http://repository.unair.ac.id/95453/3/Presepsin%20and%20Procalcitonin.pdf http://repository.unair.ac.id/95453/ http://juri.urologi.or.id/juri/article/view/463 https://doi.org/10.32421/juri.v25i2.463 |
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id-langga.954532020-06-02T01:37:03Z http://repository.unair.ac.id/95453/ Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis Sofyan Rais Addin Tarmono Djojodimedjo Fikri Rizaldi R Medicine (General) RD Surgery Objective: To evaluate the prognostic value of presepsin and procalcitonin in patient with urosepsis. Material & Method: This is an observational prospective study. Patients who fulfilled the criteria for urosepsis at Soetomo Hospital Surabaya were enrolled. Presepsin and procalcitonin were measured at first admission. All patients were managed according to standard urosepsis therapy. At the 28th day of treatment, patients were evaluated and classified into survivor and non-survivor. The statistical analysis were tested with logistic regression test using software SPSS 23. Results: 30 urosepsis patients were included in this study with average age was 48.3 years (range 21-77 years). There were 23 survivor and 7 non-survivor. Mean presepsin values were higher in non-survivor than in survivor but the difference was not significant (4405 ± 4664 vs 4042 ± 2643, p=0.259). Mean procalcitonin value was significantly higher in non-survivor than in survivor (7.68 ± 6.81 vs 3.27 ± 2.74, p=0.013). Using the cut off value ≥2.24 ng/ml, procalcitonin can predict mortality in 28 days with sensitivity 71.4% and specificity 47.8%. Conclusion: Presepsin can not be used to determine the prognosis of urosepsis patients. Procalcitonin showed a significant correlation with outcome of urosepsis patients so it can be use to determine the prognosis of urosepsis. The Indonesian Urological Association 2018-07 Article PeerReviewed text en http://repository.unair.ac.id/95453/1/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis_compressed.pdf text en http://repository.unair.ac.id/95453/2/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis.pdf text en http://repository.unair.ac.id/95453/3/Presepsin%20and%20Procalcitonin.pdf Sofyan Rais Addin and Tarmono Djojodimedjo and Fikri Rizaldi (2018) Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis. Indonesian Journal of Urology, 25 (2). pp. 151-156. ISSN 0853-442X http://juri.urologi.or.id/juri/article/view/463 https://doi.org/10.32421/juri.v25i2.463 |
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R Medicine (General) RD Surgery Sofyan Rais Addin Tarmono Djojodimedjo Fikri Rizaldi Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
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Objective: To evaluate the prognostic value of presepsin and procalcitonin in patient with urosepsis. Material & Method: This is an observational prospective study. Patients who fulfilled the criteria for urosepsis at Soetomo Hospital Surabaya were enrolled. Presepsin and procalcitonin were measured at first admission. All patients were managed according to standard urosepsis therapy. At the 28th day of treatment, patients were evaluated and classified into survivor and non-survivor. The statistical analysis were tested with logistic regression test using software SPSS 23. Results: 30 urosepsis patients were included in this study with average age was 48.3 years (range 21-77 years). There were 23 survivor and 7 non-survivor. Mean presepsin values were higher in non-survivor than in survivor but the difference was not significant (4405 ± 4664 vs 4042 ± 2643, p=0.259). Mean procalcitonin value was significantly higher in non-survivor than in survivor (7.68 ± 6.81 vs 3.27 ± 2.74, p=0.013). Using the cut off value ≥2.24 ng/ml, procalcitonin can predict mortality in 28 days with sensitivity 71.4% and specificity 47.8%. Conclusion: Presepsin can not be used to determine the prognosis of urosepsis patients. Procalcitonin showed a significant correlation with outcome of urosepsis patients so it can be use to determine the prognosis of urosepsis. |
format |
Article PeerReviewed |
author |
Sofyan Rais Addin Tarmono Djojodimedjo Fikri Rizaldi |
author_facet |
Sofyan Rais Addin Tarmono Djojodimedjo Fikri Rizaldi |
author_sort |
Sofyan Rais Addin |
title |
Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
title_short |
Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
title_full |
Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
title_fullStr |
Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
title_full_unstemmed |
Presepsin and Procalcitonin Values to Determine The Prognosis of Urosepsis |
title_sort |
presepsin and procalcitonin values to determine the prognosis of urosepsis |
publisher |
The Indonesian Urological Association |
publishDate |
2018 |
url |
http://repository.unair.ac.id/95453/1/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis_compressed.pdf http://repository.unair.ac.id/95453/2/Presepsin%20and%20Procalcitonin%20Values%20to%20Determine%20The%20Prognosis%20of%20Urosepsis.pdf http://repository.unair.ac.id/95453/3/Presepsin%20and%20Procalcitonin.pdf http://repository.unair.ac.id/95453/ http://juri.urologi.or.id/juri/article/view/463 https://doi.org/10.32421/juri.v25i2.463 |
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1681153507836559360 |