Gambaran Histopatologi Hepar Mencit Jantan (Mus musculus) Yang Dipapar Asap Rokok Dan Diberi Ekstrak Etanol Kulit Pisang Kepok (Musa acuminata)
This research aims was to proven that ethanol extract of Kepok banana peel (Musa acuminata) could reduce liver damage at the liver histopathology of male mice (Mus musculus). This research used 20 male mice (Mus musculus) 8-12 weeks old, body weight about 20 - 25 gram, with six kinds of treatment an...
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| Summary: | This research aims was to proven that ethanol extract of Kepok banana peel (Musa acuminata) could reduce liver damage at the liver histopathology of male mice (Mus musculus). This research used 20 male mice (Mus musculus) 8-12 weeks old, body weight about 20 - 25 gram, with six kinds of treatment and 4 times of repetition. All the groups, except K- as a control group, was treated with cigarette smoke for 14 days. After that, P1 was treated with kepok banana peel extract 14 mg/kgBW, P2 was treated with kepok banana peel extract 28 mg/kgBW, and P3 was treated with kepok banana peel extract 56 mg/kgBW and K.O was treated with ascorbic acid 13 mg/kgBW for 14 days without cigarette smoke. Samples were scoring by Knodell (2000) and Klopfleisch (2013) method and analyzed with Kruskal Wallis and continued to Mann Whitney test. The results showed that at the group of P1 could reduce liver damage than the group of K+, K.O, P2 and P3. This showed that the ethanol extract of kepok banana peel (Musa acuminate) with a dose of 14 mg/Kg BW could reduce liver damage. |
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