Effect of Lead Acetate on The Concentration and Sperm Morphology in Mice BALB/C (Mus Musculus)

• Main Authors: Yeti Mareta Undaryati, Sri Agus Sudjarwo, Reny I'tishom
• Format: Book Section PeerReviewed
• Language: English; English; English
• Published: Pusat Pengkajian dan Pembangunan (PPHP) Fakultas Hukum Universitas Wijaya Kusuma Surabaya 2015
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: http://repository.unair.ac.id/95966/1/Effect%20of%20Lead%20Acetate.pdf; http://repository.unair.ac.id/95966/2/Effect%20of%20Lead%20Acetate%20on%20The%20Concentration%20and%20Sperm%20Morphology%20in%20Mice%20BALB_C%20%28Mus%20Musculus%29.pdf; http://repository.unair.ac.id/95966/5/Effect%20of%20Lead.pdf; http://repository.unair.ac.id/95966/
• Institution: Universitas Airlangga

Abstract: Air pollution is mostly dominated by motor vehicle exhaust gas. Lead is one of motor vehicle exhaust gas that is one of toxic heavy metal, one of which is a toxicant for sperm. This study was aimed to demonstrate effect of lead acetate on the concentration and sperm morphology in mice. Mice (Mus musculus) Balb/c divided into 2 groups. K group was the control group, P group was given with lead acetate 0.075 g/Kg BW 1x/day or ally for 35 days. Result, all data were normally distributed and homogeneus, then analyzed using One Way Anova test. Result showed significant difference in sperm concentration and normal -shaped sperm morphology. In conclusion, lead acetate can significant reduce sperm concentration and normal-shaped sperm morphology in mice Balb/c (Mus musculus).