Profile of antiretroviral and its outcome on patients with HIV-AIDS in Wamena Public Hospital

• Main Authors: Erwin Astha Triyono, Stefania Rany Seran, Didik Hasmono
• Format: Article PeerReviewed
• Language: English; English; English
• Published: PagePress Publications 2019
• Subjects: R Medicine; RC Internal medicine
• Online Access: http://repository.unair.ac.id/96465/1/Profile%20of%20antiretroviral%20and%20its%20outcome%20on%20patients%20with%20HIV-AIDS%20in%20Wamena%20Public%20Hospital.pdf; http://repository.unair.ac.id/96465/2/Profile%20of%20Antiretroviral%20and%20its%20outcome.pdf; http://repository.unair.ac.id/96465/3/Profile%20of%20antiretroviral%20and%20its%20outcome%20on%20patients%20with%20HIV-AIDS%20in%20Wamena%20Public%20Hospital.pdf; http://repository.unair.ac.id/96465/; https://www.pagepress.org/journals/index.php/dr/article/view/8063; https://doi.org/10.4081/dr.2019.8063
• Institution: Universitas Airlangga

In Papua, HIV/AIDS is characterized as a widespread epidemic, with a prevalence of 2.3% and a case rate of 416.91 per 100.000. The low accessibility of healthcare services is a major challenge for health services in Papua. The purpose of this study was to determine the profile of ARV use and therapy outcomes of HIV/AIDS patients at Wamena Public Hospital in Papua. This research is an observational cross-sectional retrospective study. Data was collected from the medical records of 236 patients who met the inclusion criteria. Study showed that FDC (TDF + 3TC + EFV) is the most frequently used ARV. ARV therapy improved the clinical condition of 14 patients, and 9 patients had a worsening of their clinical condition. There was an increase in CD4 cell count after 6, 12, and 24 months of ARV therapy in 76%; 55%; and 72% of patients. There were 55 adverse drug events that required a change of regimen. Based on this study, the use of antiretroviral drugs improved clinical condition, decreasing the number of IO, and increasing the patient's CD4 cell count.