Soetomo Score as a Predictor of HIV-Associated Neurocognitive Disorders

• Main Authors: Fajar Rudy Qimindra, Muhammad Hamdan, Riani Wisnujono, Yudha Haryono, Abdulloh Machin
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Hampstead Psychological Associates 2020
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: http://repository.unair.ac.id/97493/1/Soetomo%20Score%20as%20a%20Predictor%20of%20HIV-Associated%20Neurocognitive%20Disorders.pdf; http://repository.unair.ac.id/97493/2/Soetomo%20Score%20as%20a%20predictor.pdf; http://repository.unair.ac.id/97493/3/Soetomo%20Score%20as%20a%20Predictor%20of%20HIV-Associated%20Neurocognitive%20Disorders.pdf; http://repository.unair.ac.id/97493/; https://www.psychosocial.com/article/PR200736/10774/; https://doi.org/10.37200/IJPR/V24I2/PR200736
• Institution: Universitas Airlangga

Background HIV-Associated Neurocognitive Disorders (HAND)wasone of theneurological complicationsof HIVinfection. However, there were no biomarkers have been sufficiently validated for prognosis HAND. Objective: To develop a scoring system and determine prognostic values of Soetomo Score as Predictor of HIV-Associated Neurocognitive Disorders (SSP HAND). Methods: The case-control study was performed at the UPIPI out-patient clinic. The examination is performed using MoCa-Ina.Eight parameters which were possible to be a predictor of HAND were analyzed by bivariate and multivariate. Results were analyzed using calibration test and discrimination test produced Area Under Curve (AUC) value. The cut-off point could make identification of good and bad prognostics. Results: The equation of SSP HAND was Y=-4.164+1.249 score total of SSP HAND. AUC value of this score was 80.9% (95% CI=71.1%-90.6%). The value of SSP HAND was ≥3.5,it means that the sensitivity was74,4% and the specificity was79.5%. Subject with score 0–3 had good prognostic while score 4–5 had bad prognostic. Conclusion: Value of SSP HAND ≥3.5 could make a good prediction of HAND.