Respon Imun Mencit (Mus musculus) yang Divaksin Brucella Abortus Strain RB 51 dan Diinfeksi Brucella suis terhadap Histopatologi Limpa

• Main Authors: Maria Gladis Bupu Meze, Emy Koestanti Sabdoningrum, Sri Chusniati, Lilik Maslachah
• Format: Article PeerReviewed
• Language: Indonesian; Indonesian
• Published: Fakultas Kedokteran Hewan Universitas Airlangga 2017
• Subjects: SF405.5-407 Laboratory animals; SF811-909 Veterinary medicine of special organs, regions, and systems
• Online Access: http://repository.unair.ac.id/97835/1/Bukti%20C%2021%20Respon%20Imun%20Mencit%20%28Mus%20musculus%29%20....pdf; http://repository.unair.ac.id/97835/2/Peer%20review%20C%2021%20Respon%20Imun%20Mencit%20%28Mus%20musculus%29%20....pdf; http://repository.unair.ac.id/97835/
• Institution: Universitas Airlangga

The purpose of this study was to knowthe number and diameter of white pulp of the spleen of mice (Mus musculus) by vaccinated Brucella abortus Strain RB5 l and infected Brucella suis. Eighteen mice were divided into three treatment groups which each group consists of six mice, PO- as negative control was given NaCl by intramuscular injection, meanwhile PO+ as positive control was infected with Brucella suis lx l 08CFU/ml and Pl was vaccinated by Brucella abortus strain RB5 l 0,I ml and infected by Brucella suislxl08CFU/ml, and then sacrified at tenth week. The data of the number and diameter of white pulp of the spleen was examine with Nikkon H600L microskop. Then, the data analyzed using ANOVAtest and continued by HSDtest. The result of this study showed there was significant (p<0,05) different between negative control and treatment groups but not significant different with positive control. Keywords : Brucella abortus strain RB5 l, Brucella suis, mice, the number of white pulp, diameter white pulp