The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients
This study is aimed to compare the difference of neutropenia with peripheral neuropathy condition, after administration of 3 hours and 24 hours Paclitaxel infusion in adjuvant therapy with PaclitaxelCarboplatin toward patient with ovarian carcinoma. The method that used was experimental research wi...
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Publishing Group "Interdisciplinary Academy of Pain Medicine"
2019
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Online Access: | https://repository.unair.ac.id/98646/1/The%20Comparison.pdf https://repository.unair.ac.id/98646/2/The%20Comparison%20of%20Neutropenia.pdf https://repository.unair.ac.id/98646/3/The%20Comparison%20of%20Neutropenia%20and%20Peripheral%20Neuropathy%20Condition%20as%20an%20Impact%20of%203-hours%20and%2024-hour%20Paclitaxel%20Infusion%20of%20Paclitaxel-Carboplatin%20Chemotherapy%20on%20Ovarian%20Cancer%20Patients.pdf https://repository.unair.ac.id/98646/7/Bukti%20Etik%20No%204.pdf https://repository.unair.ac.id/98646/ https://painmedicine.org.ua/index.php/pnmdcn/article/view/197 https://doi.org/10.31636/pmjua.v4i2.3 |
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id-langga.986462022-06-07T04:43:57Z https://repository.unair.ac.id/98646/ The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients Primandono Perbowo, - Brahmana Aksandar, - Sunjoto, - Ratna Soebadi, - Achmad Bashori, - R Medicine (General) RG Gynecology and obstetrics RG1-991 Gynecology and obstetrics This study is aimed to compare the difference of neutropenia with peripheral neuropathy condition, after administration of 3 hours and 24 hours Paclitaxel infusion in adjuvant therapy with PaclitaxelCarboplatin toward patient with ovarian carcinoma. The method that used was experimental research with samples randomized after consecutively recruited based on inclusive criteria. Before and every after chemotherapy, NCS was performed and differential count laboratories’ test and then analysed with Ttest and Chisquare test. The result showed that from three times administration of 3 hours PaclitaxelCarboplatin infusion group, the neutropenia condition after first up to third chemotherapy was 20 %, 30 %, 30 %, and the peripheral neuropathy condition was 30 %, 60 %, 50 % respectively. Meanwhile, in 24 hours PaclitaxelCarboplatin infusion group, the incident of neutropenia after first up to third chemotherapy was 40 %, 50 %, 40 %, and the incident of peripheral neuropathy was 20 %, 20 %, 20 % respectively. The statistic result was p > 0.05. Hence, there was no significant difference in neutropenia and peripheral neuropathy incident on two study group. Publishing Group "Interdisciplinary Academy of Pain Medicine" 2019 Article PeerReviewed text en https://repository.unair.ac.id/98646/1/The%20Comparison.pdf text en https://repository.unair.ac.id/98646/2/The%20Comparison%20of%20Neutropenia.pdf text en https://repository.unair.ac.id/98646/3/The%20Comparison%20of%20Neutropenia%20and%20Peripheral%20Neuropathy%20Condition%20as%20an%20Impact%20of%203-hours%20and%2024-hour%20Paclitaxel%20Infusion%20of%20Paclitaxel-Carboplatin%20Chemotherapy%20on%20Ovarian%20Cancer%20Patients.pdf text en https://repository.unair.ac.id/98646/7/Bukti%20Etik%20No%204.pdf Primandono Perbowo, - and Brahmana Aksandar, - and Sunjoto, - and Ratna Soebadi, - and Achmad Bashori, - (2019) The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients. Pain Medicine Journal, 4 (2). pp. 41-52. ISSN 2414-3812 https://painmedicine.org.ua/index.php/pnmdcn/article/view/197 https://doi.org/10.31636/pmjua.v4i2.3 |
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R Medicine (General) RG Gynecology and obstetrics RG1-991 Gynecology and obstetrics Primandono Perbowo, - Brahmana Aksandar, - Sunjoto, - Ratna Soebadi, - Achmad Bashori, - The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
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This study is aimed to compare the difference of neutropenia with peripheral neuropathy condition, after administration of 3 hours and 24 hours Paclitaxel infusion in adjuvant therapy with PaclitaxelCarboplatin toward patient with ovarian carcinoma. The method that used was experimental research with samples randomized after consecutively recruited based on inclusive criteria. Before and every after chemotherapy, NCS was performed and differential count laboratories’ test and then analysed with Ttest and Chisquare test. The result showed that from three times administration of 3 hours PaclitaxelCarboplatin infusion group, the neutropenia condition after first up to third chemotherapy was 20 %, 30 %, 30 %, and the peripheral neuropathy condition was 30 %, 60 %, 50 % respectively. Meanwhile, in 24 hours PaclitaxelCarboplatin infusion group, the incident of neutropenia after first up to third chemotherapy was 40 %, 50 %, 40 %, and the incident of peripheral neuropathy was 20 %, 20 %, 20 % respectively. The statistic result was p > 0.05. Hence, there was no significant difference in neutropenia and peripheral neuropathy incident on two study group. |
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Article PeerReviewed |
author |
Primandono Perbowo, - Brahmana Aksandar, - Sunjoto, - Ratna Soebadi, - Achmad Bashori, - |
author_facet |
Primandono Perbowo, - Brahmana Aksandar, - Sunjoto, - Ratna Soebadi, - Achmad Bashori, - |
author_sort |
Primandono Perbowo, - |
title |
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
title_short |
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
title_full |
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
title_fullStr |
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
title_full_unstemmed |
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients |
title_sort |
comparison of neutropenia and peripheral neuropathy condition as an impact of 3-hours and 24-hour paclitaxel infusion of paclitaxel-carboplatin chemotherapy on ovarian cancer patients |
publisher |
Publishing Group "Interdisciplinary Academy of Pain Medicine" |
publishDate |
2019 |
url |
https://repository.unair.ac.id/98646/1/The%20Comparison.pdf https://repository.unair.ac.id/98646/2/The%20Comparison%20of%20Neutropenia.pdf https://repository.unair.ac.id/98646/3/The%20Comparison%20of%20Neutropenia%20and%20Peripheral%20Neuropathy%20Condition%20as%20an%20Impact%20of%203-hours%20and%2024-hour%20Paclitaxel%20Infusion%20of%20Paclitaxel-Carboplatin%20Chemotherapy%20on%20Ovarian%20Cancer%20Patients.pdf https://repository.unair.ac.id/98646/7/Bukti%20Etik%20No%204.pdf https://repository.unair.ac.id/98646/ https://painmedicine.org.ua/index.php/pnmdcn/article/view/197 https://doi.org/10.31636/pmjua.v4i2.3 |
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1735493358295449600 |