Comparison of Periturbal Infiltration of Ropivacain and Placebo in Percutaneous Nephrolitholapaxy for post operative analgesia at Soetomo Hospital Surabaya

• Main Authors: Arley Sadra Telussa, Dedi Susila, Lukman Hakim, Doddy M. Soebadi
• Format: Article PeerReviewed
• Language: English; English; English
• Published: The Indonesian Urological Association 2018
• Subjects: R Medicine (General); RC870-923 Diseases of the genitourinary system. Urology
• Online Access: http://repository.unair.ac.id/99136/1/Comparison%20of%20peritubal%20infiltration%20of%20ropivacain%20and%20Placebo%20in%20percutaneous%20nephrolitholapaxy%20for%20post%20operative%20analgesia%20at%20soetomo%20hospital%20surabaya.pdf; http://repository.unair.ac.id/99136/2/Comparison%20of%20Peritubal.pdf; http://repository.unair.ac.id/99136/3/Comparison%20of%20peritubal%20infiltration%20of%20ropivacain%20and%20Placebo%20in%20percutaneous%20nephrolitholapaxy%20for%20post%20operative%20analgesia%20at%20soetomo%20hospital%20surabaya.pdf; http://repository.unair.ac.id/99136/; http://juri.urologi.or.id/juri/article/view/467; https://doi.org/10.32421/juri.v25i2.467
• Institution: Universitas Airlangga

Objective: To observe the effects of ropivacain peritubal infiltration in reducing postoperative pain and analgesic requirements postoperatively in patients underwent percutaneous nephrolithotomy (PNL). Material & method: Double blind randomized controlled trial on 32 patients with renal stone who underwent PNL at Soetomo General Hospital Surabaya from February until August 2017, divided into 2 groups. Experimental group (A) who received peritubal infiltration of ropivacain pre-operative, and control (placebo) group (B) Evaluation using Wong Baker pain score 2 hour post operation, time from operation until first rescue analgesia, and total analgesia given in first 24 hours. Result: Mean age was 51.81 ± 9.13 and 49.31 ± 10.53 years in group A and B respectively. Mean operation time 49.31 ± 10.53 and 89.69 ± 17.74 hours in group A and B respectively. There was no significant difference in stone complexity, nephrostomy placement and stenting between two groups. There was no significant difference of Wong Baker pain score 2 hours post operation between group A and B (p 0.72). There was no significant difference in total analgesia in the first 24 hours between group A and B (p 0.48). The time of first rescue analgesia demand was significantly longer in the experimental group (p 0.00). Conclusion: Peritubal infiltration of ropivacain in percutaneous nephrolitholapaxy is safe and effective to prolong the need of first rescue analgesia in post operative pain management which result in patients convenience.